… gas that can dilate the pulmonary vasculature. This gas has … , permissive hypercapnia and
measures to reduce pulmonary … We did not perform a subgroup analysis of reversal of ARDS, …

… “Gentle” ventilation strategies with permissive hypercapnia are … to reverse the ductal shunt
by elevating systemic vascular … through uncoupling nitric oxide synthase in pulmonary arterial …

… vasodilator (IPVD) therapy either in the form of nitric oxide (… target PaO 2 8kPa with permissive
hypercapnia. Where this could … pulmonary vascular resistance, reduced pulmonary arterial …

… exposure results in the down-regulation of endogenous nitric oxide synthase in the
pulmonary vascular endothelium and a reduction in guanylyl cyclase activity ( 31 ). If exogenous …

… Hypotension produced reproducible increases in pial artery … Papaverine-induced (10 −8 ,
10 −6 M) pial artery dilation … via what we have historically termed the permissive effect of NO. In …

… effects of eNOS overexpression being reversed by the non-… , such as for the treatment of
pulmonary artery hypertension. … streptozotocin-induced diabetes, indicating that increased iNOS …

… NO acts to prevent the growth and immunopathology caused by TB via S-nitrosylation and
… Drug efficacy may be improved for pulmonary TB by using inhaled delivery. As with all new …

… is a permissive post-translational modification, leading to an … dysfunction can be reversed
by improving BH 4 availability in … in lung vasculature and its activity is increased in pulmonary …

… pulmonary vascular resistance and mean pulmonary artery … Permissive hypercapnia is a
strategy used in the … attempt to decrease ventilator induced lung injury caused by barotrauma or …

… Many authors have discouraged permissive hypercapnia in … This vasoconstriction may be
reversed using iNO (240). In contrast, … Nitric oxide deficiency and endothelial dysfunction in …