… The endogenous opioid system is intimately involved in both … showing that opioid antagonists
prevent food-seeking and … to anticipatory food cues, which can consequently inhibit urges …

… ) and inhibitory (often GABAergic) transmission and postsynaptic … , while KORs inhibit both
GABA and glutamate transmission, … that prevents the strong feedforward inhibition of CA3-CA2 …

… , we observed a sustained inhibition of GCaMP activity (lasting … be activated via retrograde
transmission. To determine whether … The cut-off was set to 10 s after immersion to prevent …

… Binge eating in humans is driven by hedonic properties of food, … group with restricted access
to both commodities (4SUC/4F). … food intake or seeking responses when access to palatable …

… systemic opioid antagonist administration was found to prevent the … well as disrupting inhibitory
control over food-seeking. The … Hence, a gradient of μ-opioid sensitivity is apparent in the …

… opioids to the OFC can alter the hedonic reaction to food … that mu-opioids affect inhibitory
synaptic transmission within the … that enhancing endogenous opioid levels by preventing their …

… appetite, as they send a stop-food signal to the brain secreting … Both medications were able
to inhibit food intake, and some … novel µ opioid receptor antagonist, on food seeking behavior …

… contribute to inhibitory control deficits will be discussed. Evidence has accrued to suggest that
excessive intra-PFC μ-opioid receptor (μ… prevents both food seeking and binge-like eating. …

… CB1 or μ opioid receptors inhibit adenylate cyclase (AC) … Both effects were dependent upon
dopamine transmission in the mPFC as systemic blockade of dopamine receptors prevented …

… , which has prevented the development of therapies to maximize and sustain opioid analgesic
… Notably, we found that both DAMGO-induced inhibition and LTP were completely lost in …