Advances in Flavonoid Research: Sources, Biological Activities, and Developmental Prospectives

B Hao, Z Yang, H Liu, Y Liu, S Wang - Current Issues in Molecular …, 2024 - mdpi.com
… the phosphorylation of acetyl coenzyme A carboxylesterase (… These flavonoids significantly
inhibited the production of … closely related to the inhibition of phosphorylated forms of NF-κB …

Biologically active prenylated flavonoids from the genus Sophora and their structure–activity relationship—A review

M Boozari, S Soltani, M Iranshahi - Phytotherapy research, 2019 - Wiley Online Library
flavonoids with hydroxyl groups at the C3 and C6 and prenyl moieties at C8 site are able to
inhibit human carboxylesterase … a series of tyrosine phosphorylation events that leads to the …

Dietary chicory root and chicory inulin trigger changes in energetic metabolism, stress prevention and cytoskeletal proteins in the liver of growing pigs–a proteomic …

A Lepczyński, A Herosimczyk, M Ożgo… - Journal of animal …, 2017 - Wiley Online Library
… The phosphorylation-induced activation of AMPK regulates … include ApoAI, CES1 (liver
carboxylesterase 1), GPD1 (… (chicory is a source of these flavonoids) were added to the cell …

Analysis of mulberry leaf components in the treatment of diabetes using network pharmacology

Q Ge, L Chen, M Tang, S Zhang, L Liu, L Gao… - European journal of …, 2018 - Elsevier
… The alkaloids, flavonoids, and polysaccharides in mulberry leaves impart … The phosphorylation
of the Ser473 site by AKT via PI3K is key to AKT activation. Negative regulators that inhibit

Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer's disease …

GF Makhaeva, NP Boltneva, SV Lushchekina… - Bioorganic & Medicinal …, 2018 - Elsevier
… that chromones and their derivatives (eg, flavonoids) are known to play important roles as
… To determine the inhibitory activity of the synthesized compounds toward carboxylesterase (…

Porcine cytochrome P450 3A: current status on expression and regulation

MK Rasmussen - Archives of Toxicology, 2020 - Springer
… alternative splicing, posttranslational modification like phosphorylation, and epigenetic control
via … , the mode of inhibition was determined as competitive. Other major flavonoids such as …

Psoralea corylifolia L: Ethnobotanical, biological, and chemical aspects: A review

F Alam, GN Khan, MHHB Asad - Phytotherapy Research, 2018 - Wiley Online Library
… belongs to coumarins, flavonoids, and meroterpenes groups. … dependent inhibitory effect on
the human carboxylesterase 1 … ) stimulated liver kinase B1 and AMPKα phosphorylation in a …

Pharmacological review of isobavachalcone, a naturally occurring chalcone

M Wang, L Lin, JJ Lu, X Chen - Pharmacological research, 2021 - Elsevier
… Gu Zhi include coumarins, flavonoids, meroterpenes, benzofuran… IBC bonded the active
pocket of carboxylesterase 1 (CES1), … of STAT6 phosphorylation and subsequent inhibition of the …

[HTML][HTML] A molecular insight into the role of antioxidants in nonalcoholic fatty liver diseases

D Ezhilarasan, T Lakshmi - Oxidative Medicine and Cellular …, 2022 - hindawi.com
… in βoxidation and oxidative phosphorylation in mitochondria, … of the Nrf2/carboxylesterase 1
signaling pathway involved in the … This study suggests that flavonoid compounds can induce …

[PDF][PDF] Lantana rhodesiensis Moldenke: traditional uses, phytochem constituents and pharmacological activities

BM Jean, MR Nâ, BM Jean - researchgate.net
… We note that flavonoids represent the low value in term of … They act are by cytotoxicity or
phosphorylation on the cells [3-… the carboxylesterase inhibition showed 56.72 % inhibition, …