… for their potential to treat neoplastic disorders. Some of these … -induced lung inflammation to
corticosteroid therapy indicate … a possible mechanism, at least in part, in inducing lung injury …

… Preclinical research shows the potential for therapies … Radiation therapy induced pulmonary
symptoms are seen in … , functional, and radiographic endpoints individually (Table 1). The …

… clinical endpoints and their potential to serve as primary … , surrogate endpoints are expected
to predict clinical benefit or harm [6]. … , incurable diseases, TTNT is a meaningful endpoint for …

… endpoints used in IO trials to date and potential optimal … trials to focus on the patient
experience, their symptoms, and … or harm from immunotherapy; HRQOL and PRO endpoints can …

… a potential turning point in designing future IPF clinical trials … or external symptoms, there
are potential extrapulmonary … Instead, they are anticipated to predict clinical benefit or harm…

… Instead, we will discuss in more detail potential risks and … of a systemic inflammatory response
syndrome (SIRS). Due to … tissue damage (trauma) and inflammation with the potential to …

… not reflect early signs of meaningful patient benefit or harm. … as end points in oncology clinical
trials are the toxicities of the … The development of composite end points has the potential to …

… demonstrated delayed, potentially fatal lung injury in the NHP. … The primary endpoint in this
study was mortality at 180 d post-… septal thickening are three quantifiable CT parameters for …

… Knowledge of the potential benefits and risks associated with … efficacy, evaluated according
to the primary end points that … measuring the risk of harm from anticancer therapy, is based …

… for its harm and disease risk reduction potential, which is … relevance to lung diseases and
cancer, as chronic bronchitis … on cellular and molecular endpoints linked to carcinogenesis. For …