The vascular-dependent and-independent actions of calcitonin gene-related peptide in cardiovascular disease

F Argunhan, SD Brain - Frontiers in Physiology, 2022 - frontiersin.org
Calcitonin gene-related peptide (CGRP) is a 37 amino acid … with positive-ionotropic and
-chronotropic effects. It has been … -inotropic, -chronotropic and -lusitropic responses in the heart. …

Protective role of α-calcitonin gene-related peptide in cardiovascular diseases

A Kumar, JD Potts, DJ DiPette - Frontiers in physiology, 2019 - frontiersin.org
… to date and has inotropic and chronotropic effects. Using … cardiovascular diseases such
as heart failure, experimental … reverse the adverse effects of hypertension and heart failure in …

The role of calcitonin gene related peptide (CGRP) in neurogenic vasodilation and its cardioprotective effects

Z Kee, X Kodji, SD Brain - Frontiers in physiology, 2018 - frontiersin.org
Calcitonin gene-related peptide is a 37 amino acid peptide, produced by alternative splicing
… decreases afterload and increases inotropy, which is protective in heart failure. Finally, …

[HTML][HTML] Calcitonin gene-related peptide exerts inhibitory effects on autophagy in the heart of mice

AZ Schavinski, J Machado, HJN Morgan… - Peptides, 2021 - Elsevier
… the acute effects of CGRP on autophagy and the related signaling pathways in the heart mice
… The calcitonin gene-related peptide (CGRP) is a neuropeptide composed of a sequence of …

Cardioprotective effects of calcitonin gene-related peptide in isolated rat heart and in H9c2 cells via redox signaling

F Tullio, C Penna, K Cabiale, S Femminò… - Biomedicine & …, 2017 - Elsevier
Calcitonin gene-related peptide (CGRP) is a transmitter originated by tissue-specific splicing
of the calcitonin gene … , which increases the contractility of the heart (positive inotropy) [44]. …

Blood Pressure Normalization–Independent Cardioprotective Effects of Endogenous, Physical Activity–Induced αCGRP (α Calcitonin Gene-Related Peptide) in …

T Skaria, KJ Mitchell, O Vogel, T Wälchli… - Circulation …, 2019 - Am Heart Assoc
Effect of αCGRP (α calcitonin gene-related peptide) treatment on myofibroblast … It has
positive chronotropic and inotropic effects and stimulates physiological cardiomyocyte …

The Neuropeptide α-Calcitonin gene-related peptide as the Mediator of Beneficial effects of Exercise in the Cardiovascular System

T Skaria, J Vogel - Frontiers in Physiology, 2022 - frontiersin.org
… plasma concentration of α-calcitonin gene-related peptide (αCGRP), a 37-amino acid …
chronotropy and inotropy but also by exerting direct hormonal protective effects on the heart to …

Alpha-calcitonin gene related peptide: new therapeutic strategies for the treatment and prevention of cardiovascular disease and migraine

A Kumar, M Williamson, A Hess, DJ DiPette… - Frontiers in …, 2022 - frontiersin.org
… stimulation of cardiomyocytes triggers positive ionotropic effects via the cAMP/PKA … ionotropic
and chronotropic effects in the cardiac cells, but these results were diminished when hearts

Low Serum Calcitonin Gene-Related Peptide Level is Associated with Severity of Coronary Stenosis

XF Dong, JX Zhong, YM Yan, MF Ye… - Clinical and …, 2021 - utpjournals.press
Calcitonin gene-related peptide (CGRP) is a neuropeptide that is mainly recognized for its
Inotropic and lusitropic effects of calcitonin gene-related peptide in the heart. Am J Physiol. …

[PDF][PDF] The Neuropeptide฀-Calcitonin Gene-Related Peptide as the Mediator of Beneficial Effects of Exercise in the Cardiovascular System

T Skaria, J Vogel - 2022 - scholar.archive.org
… -calcitonin gene-related peptide (฀CGRP), a 37-amino acid … and inotropy but also by
exerting direct hormonal protective … in patients with coronary heart disease and healthy controls. …