… findings suggested a deficiency in osteoblast development, recruitment, or efficiency in the
setting of MDS, suggesting that the function of mesenchymal … and a lack of myelodysplasia, …

… This review may help improve existing knowledge regarding … of MDS and enable new targets
for the treatment of MDS to be … results indicated that dysfunctional MSCs derived from MDS …

… Mesenchymal stromal cells (MSCs) are a principal … We had excluded certain MDS-MSCs
from this analysis due to lack of … In correlating our experimental results with clinical findings, …

… -MDS stromal microenvironment as compared to those from healthy subjects. At the molecular
level… Contradicting some reports (4, 14), our results revealed that although LR-MDS MSCs …

… Dicer1 in mesenchymal/osteoprogenitor cells resulted in a MDS phenotype … Insufficient
stromal support in MDS results from molecular and functional deficits of mesenchymal stromal …

… in vitro–expanded mesenchymal stromal cells, into the marrow … WNT signaling in mesenchymal
cells in MDS may result from … seems to be insufficient experimental support for the view …

… MSCs in MDS showing functional and molecular alterations … healthy microenvironment is
not sufficient to improve cytopenias… vivo studies revealed that MDS pathogenesis results from a …

… Overall, our results elucidated that MDS-MSCs and AML-… mesenchymal stromal cell from
myelodysplastic syndrome … Molecular alterations in bone marrow mesenchymal stromal cells …

… Our findings establish transforming growth factor β1 as a … substantially to the inadequate
hematopoiesis in MDS and AML… revealed a specific molecular signature of MDS- and AML-…

… , as well as for molecular functions associated with transcription regulation (… Insufficient
stromal support in MDS results from molecular and functional deficits of mesenchymal stromal …