… insulin stimulated glucose oxidation, we determined directly what … insulin-stimulation of
mitochondrial AKT is a prerequisite to … the direct insulin stimulation of PDH and glucose oxidation, …

… insulin signalling may also directly contribute to mitochondrial structural remodelling in the
heart… complex (PDC) also stimulates glucose oxidation, which due to the higher P/O ratio of …

… suppression of mitochondrial fatty acid oxidation in the heart, … Thus, short-term insulin
stimulation might direct FA into synthetic … source of FA that is oxidized by the beating heart (37). …

… that insulin resistance in the context of heart failure directly … Insulin may also directly regulate
mitochondrial metabolism … Insulin stimulation of the heart activates PI3K and Akt, which …

… Cardiac FA uptake via FAT-CD36 is stimulated by insulin or AMP-activated kinase (AMPK)
[… acyl CoA [38] and directly shuttled to the mitochondria to start β-oxidation. The long-chain …

… insulin signalling through Akt directly acting on mitochondrial PDH could explain these … In
this study, we showed that the impaired insulin stimulation of glucose oxidation translates into …

… Impairment of insulin metabolic signalling also inhibits GLUT4 … in diabetic hearts may
exceed the capacity of mitochondrial … directly prompt oxidative stress by increasing NADPH …

… insulin signaling in heart plays in the pathogenesis of DCM. … that hyperglycemia can directly
stimulate the production of … diabetic hearts are the direct result of impaired insulin signaling …

… We sought in vivo evidence that insulin stimulates cardiac … vivo heart model, insulin-induced
increases in glucose oxidation … acid oxidation and activation of PDH by insulin are directly …

… actions on glucose metabolism via direct stimulation of hepatic … Other studies have revealed
T3 stimulates mitochondrial … to improve glucose metabolism in the heart during insulin …