This study aimed to investigate the potential association between night-shift work and insulin
resistance as well as potential serum molecular biomarkers of cardiovascular diseases
(CVD) progression; specifically, highly sensitive-C-reactive protein (hs-CRP),
thrombospondin 1 (TSP-1), matrix metalloproteinase-9 (MMP-9), plasminogen activator
inhibitor-1 (PAI-1) and oxytocin as well as homeostatic model assessment-insulin resistance
[HOMA-IR] index. In a cross-sectional design, demographic data, clinical parameters, and …

Methods: In a cross-sectional design, demographic data, clinical parameters, and working
patterns data were documented for daytime (n= 59) and night-shift (n= 69) working
employees in Jordan University Hospital. The biomarkers serum levels were measured by
enzymatic assay procedure and compared between both groups. The correlation between
the duration, and the number of night shift was also evaluated. Results: Compared with
daytime workers, night-shift workers displayed higher levels of insulin resistance index …