[HTML][HTML] Insulin-like growth factor-1 (Igf1) signaling responses to food consumption after fasting in the Pacific rockfish Sebastes carnatus

TV Bersin, HM Mapes, ML Journey… - … and Physiology Part A …, 2023 - Elsevier
Fish adjust rates of somatic growth in the face of changing food consumption. As in other
vertebrates, growth in fish is regulated by the growth hormone (Gh)/insulin-like growth factor-
1 (Igf1) endocrine axis, and changes in food intake impact growth via alterations to Gh/Igf1
signaling. Understanding the time course by which the Gh/Igf1 axis responds to food
consumption is crucial to predict how rapidly changes in food abundance might lead to
altered growth dynamics. Here, we looked at the response times of plasma Igf1 and liver Igf1 …
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