[HTML][HTML] Adipose tissue and skeletal muscle insulin-mediated glucose uptake in insulin resistance: role of blood flow and diabetes

E Ferrannini, P Iozzo, KA Virtanen, MJ Honka… - The American journal of …, 2018 - Elsevier
… was reduced in obese subjects (2). Subsequent studies in other … uptake in insulin resistance
and type 2 diabetes (5). … An important action of insulin on fat cells is to restrain lipolysis, both …

Muscle and adipose tissue insulin resistance: malady without mechanism?

DJ Fazakerley, JR Krycer, AL Kearney… - Journal of Lipid …, 2019 - ASBMB
… of impaired glucose tolerance and impaired fasting glucose. … Insulin action and resistance
in obesity and type 2 diabetes. … (TAG) stores in adipose tissue (lipolysis) provide substrates for …

100th anniversary of the discovery of insulin perspective: insulin and adipose tissue fatty acid metabolism

AC Carpentier - American Journal of Physiology …, 2021 - journals.physiology.org
insulin-mediated suppression of adipose tissue lipolysis is the … hepatic, not skeletal muscle
or adipose tissue insulin sensitivity … post-oral glucose tolerance test (OGTT) plasma glycerol …

Insulin resistance in type 2 diabetes

M Roden, KF Petersen, GI Shulman - Textbook of diabetes, 2024 - Wiley Online Library
… of glucose tolerance preceding type 2 diabetes comes from … concentrations [47] in skeletal
muscle of type 2 diabetes … within adipose tissue, inhibit insulin- mediated lipolysis in white …

Is insulin resistance tissue-dependent and substrate-specific? The role of white adipose tissue and skeletal muscle

D Calderón-DuPont, I Torre-Villalvazo… - Biochimie, 2023 - Elsevier
… Although obesity is the result of adipose tissue expansion, it is … in adipose tissue impairs
whole body glucose tolerance [26]. … of glycerol by lipolysis is not recaptured by adipose tissue, …

Insulin: The master regulator of glucose metabolism

L Norton, C Shannon, A Gastaldelli, RA DeFronzo - Metabolism, 2022 - Elsevier
… protein, skeletal muscle function is heavily reliant on the insulin-mediated uptake of glucose
and … through primary effects on adipose tissue lipolysis and free fatty acid (FFA) availability. …

Energy metabolism of white adipose tissue and insulin resistance in humans

K Bódis, M Roden - European journal of clinical investigation, 2018 - Wiley Online Library
… impaired insulin-mediated suppression of lipolysis and … insulin sensitivity of adipose tissue
vs skeletal muscle and liver … steatosis, impaired glucose tolerance, partial lipodystrophy and …

Insulin-stimulated glucose uptake in skeletal muscle, adipose tissue and liver: a positron emission tomography study

MJ Honka, A Latva-Rasku, M Bucci… - European journal of …, 2018 - academic.oup.com
… ), BMI inversely and skeletal muscle, adipose tissue and liver … Individuals with normal weight
and normal glucose tolerance … , men had worse insulin-mediated suppression of lipolysis, …

Impaired insulin action in the liver, but not in adipose tissue or muscle, is a distinct metabolic feature of impaired fasting glucose in obese humans

KW Ter Horst, PW Gilijamse, MT Ackermans… - Metabolism, 2016 - Elsevier
… of free fatty acid suppression and skeletal muscle does not … insulin-mediated suppression of
adipose tissue lipolysis, did … increased risk for diabetes: IFG, impaired glucose tolerance (IGT…

Black African men with early type 2 diabetes have similar muscle, liver and adipose tissue insulin sensitivity to white European men despite lower visceral fat

O Bello, C Mohandas, F Shojee-Moradie, N Jackson… - Diabetologia, 2019 - Springer
… body, skeletal muscle, hepatic or adipose tissue insulin sensitivity … Insulin-mediated peripheral
glucose uptake (a), suppression … [39], suggesting that by the end of the glucose tolerance