In vitro inhibition of tumor growth by low-dose iron oxide nanoparticles activating macrophages

L Zhang, S Tan, Y Liu, H Xie, B Luo… - Journal of Biomaterials …, 2019 - journals.sagepub.com
… This study investigated the effects of Fe 3 O 4 magnetic nanoparticles on RAW264.7 cells
proliferation, migration, and inhibition of tumor growth in vitro. Fe 3 O 4 magnetic nanoparticles

Interaction between iron oxide nanoparticles (Fe3O4 NPs) and human neutrophils: Evidence that Fe3O4 NPs possess some pro-inflammatory activities

A Saafane, D Girard - Chemico-Biological Interactions, 2022 - Elsevier
… This agrees with a recent in vivo study revealing that neutrophils ingesting Fe 3 O 4 @TiO
2 … Also, our results agree with the above in vivo observations reporting that Fe 3 O 4 NPs-…

[HTML][HTML] Biological interactions of ferromagnetic iron oxide–carbon nanohybrids with alveolar epithelial cells

S Vercellino, I Kokalari, ML Cantoral, V Petseva… - Biomaterials …, 2022 - pubs.rsc.org
Iron oxide nanoparticles (IONPs) have been largely … @C biological interactions in vitro,
providing them with an in vivo-… a widely employed model of alveolar epithelial cells for a variety of …

[HTML][HTML] The use of iron oxide nanoparticles to reprogram macrophage responses and the immunological tumor microenvironment

V Mulens-Arias, JM Rojas, DF Barber - Frontiers in immunology, 2021 - frontiersin.org
… different cell types, especially their interaction with the macrophages that are involved in their
… and macrophage activation, and to reduce the OVA-expressing CT26 tumor burden in vivo (…

[HTML][HTML] Environmentally relevant iron oxide nanoparticles produce limited acute pulmonary effects in rats at realistic exposure levels

C Guo, RJM Weber, A Buckley, J Mazzolini… - International Journal of …, 2021 - mdpi.com
vitro and in vivo in the alveolar macrophage population, but not in the epithelial cells of the
alveolar … relate more specifically to the interactions between particles and respiratory tissues. …

Delivery of magnetic nanoparticles to lung cancer cells via polarized macrophages: A riveting tale of a bio-inspired phenomenon

VV Agnihotri, AP Gorle - Medical Hypotheses, 2023 - Elsevier
… of iron and macrophages, in-vitro internalization of iron … At the beginning of tumorigenesis,
alveolar macrophages (AMs) are … interaction of iron and macrophages, the potential of in-vitro

[HTML][HTML] The intrinsic biological identities of iron oxide nanoparticles and their coatings: unexplored territory for combinatorial therapies

V Mulens-Arias, JM Rojas, DF Barber - Nanomaterials, 2020 - mdpi.com
… Over the last 20 years, iron oxide nanoparticles (IONPs) have … the complex dynamics of
their interaction with biological systems (… , IONPs also interact with different cell types in vivo, a …

[HTML][HTML] Modulation of pulmonary toxicity in metabolic syndrome due to variations in iron oxide nanoparticle-biocorona composition

L Xia, S Alqahtani, CR Ferreira, UK Aryal, K Biggs… - Nanomaterials, 2022 - mdpi.com
… and inflammatory responses were evaluated in vitro to determine the contribution of …
within alveolar macrophages demonstrating that they are a primary cell type interacting with …

Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages

CS Nascimento, ÉAR Alves, CP de Melo… - …, 2021 - Future Medicine
… mice In vitro: Fe3O4-OVA activated macrophages to M1 phenotype with release of TNF-α. In
… by IONPs started with the interaction of nanoparticles with macrophage surface receptors, …

Immunological effects of iron oxide nanoparticles and iron-based complex drug formulations: Therapeutic benefits, toxicity, mechanistic insights, and translational …

A Shah, MA Dobrovolskaia - … : Nanotechnology, Biology and Medicine, 2018 - Elsevier
… has been given to the interactions between iron oxide-based … , they are known as alveolar
macrophages and osteoclasts, … , an in vivo study with cross-linked iron oxide nanoparticles