… of VEGFR-2 with Ig domain 5 of VEGFR-1. The full-length D7(… receptor trafficking: Insights
from a computational model. PLOS … reveals in vivo membrane protein interactions. Integr. Biol. …

… In this study, we have developed a novel computer model for … receptor 1 (VEGFR1), and
neuropilin-1 and 2 (NRP1 and … This is a very stringent requirement in any in vivo setting, …

… in addition to binding neuropilins, co-receptors to the VEGFRs. … While computational models
have examined VEGF isoforms … elucidated that VEGF isoform patterning observed in vivo […

… depletion in vitro, … interacting with high affinity to two transmembrane bound cell surface
receptor families; the VEGFR family of tyrosine kinase receptors, notably VEGFR-1 and VEGFR-2…

… VEGF is of particular interest after a traumatic brain injury (TBI), as it re-… a computational
model that quickly simulates vessel growth and recovery by coupling VEGF and its interactions …

… Interactions of VEGF isoforms with VEGFR-1, VEGFR-2, and neuropilin in vivo: a computational
model of human skeletal … VEGF overexpression in skeletal muscle induces angiogenesis …

… A combination of genetic and computational models has revealed … , both neuropilins can
bind to different VEGF isoforms pos… by downregulating VEGFR-2 and upregulation of VEGFR-1 …

… These include alternatively spliced VEGF receptor-2 (soluble VEGFR-2), tumor … human IL-8
(rhIL-8) under physiologic concentrations proved to be a potent stimulator of CNV in vivo [65,…

… termed VEGFR-1, VEGFR-2, and VEGFR-3 [59]. Some … to non-tyrosine kinase receptors
called neuropilin (NRP) family, … of VEGF in-vitro has a correlation with in-vivo aggressiveness of …

… Table 3: Summary of in vitro binding constants for the … but its activation indicates the interaction
of endothelial cells with … VEGFR-1 and VEGFR-2 agonists that can replace VEGF. Natural …