Antioxidant genes and susceptibility to air pollution for respiratory and cardiovascular health
E Fuertes, DA van der Plaat, C Minelli - Free Radical Biology and Medicine, 2020 - Elsevier
… in the lower respiratory tract [23] and translocate into the circulation to cause cardiovascular
… GxE interaction effects between PM 2.5 and antioxidant genes for HRV were assessed in …
… GxE interaction effects between PM 2.5 and antioxidant genes for HRV were assessed in …
[HTML][HTML] Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individuals
CA Melbourne, AM Erzurumluoglu, N Shrine… - Environment …, 2022 - Elsevier
… interaction effect for any statistically significant signal, we present the association between
lung function trait and air pollution … the most commonly evaluated antioxidant genes (for which …
lung function trait and air pollution … the most commonly evaluated antioxidant genes (for which …
[HTML][HTML] Air pollution and oxidative stress in adults suffering from airway diseases. Insights from the Gene Environment Interactions in Respiratory Diseases (GEIRD) …
… to air pollution may increase systemic oxidative stress levels in people suffering from airway
… and large surface, lungs are further equipped with an extracellular antioxidant defence …
… and large surface, lungs are further equipped with an extracellular antioxidant defence …
[HTML][HTML] Oxidative stress and air pollution: its impact on chronic respiratory diseases
MP Sierra-Vargas, JM Montero-Vargas… - International Journal of …, 2023 - mdpi.com
… in the pathophysiology of respiratory tract diseases (Figure 1). … the primary antioxidant
defenses of the respiratory system, and … factors, such as genetics and environmental exposures to …
defenses of the respiratory system, and … factors, such as genetics and environmental exposures to …
Schoolchildren's antioxidation genotypes are susceptible factors for reduced lung function and airway inflammation caused by air pollution
BY Chen, CH Chen, YC Chuang, H Kim, Y Honda… - Environmental …, 2016 - Elsevier
… exposure to ambient air pollutants and changes in lung function and nasal inflammation among
… Second, this study examined gene-environment interaction, by choosing a model where …
… Second, this study examined gene-environment interaction, by choosing a model where …
An update on immunologic mechanisms in the respiratory mucosa in response to air pollutants
… a role for antioxidants in normalizing these negative effects. Genetic variants in genes important
in epithelial cell function … for air pollution in the respiratory mucosa are the airway surface …
in epithelial cell function … for air pollution in the respiratory mucosa are the airway surface …
[HTML][HTML] Associations of short-term PM2. 5 exposures with nasal oxidative stress, inflammation and lung function impairment and modification by GSTT1-null genotype …
B Sun, J Song, Y Wang, J Jiang, Z An, J Li… - Environmental …, 2021 - Elsevier
… a major urban air pollutant worldwide. Its effects on the respiratory system of the susceptible
… Finally, the interaction between GST genes and other antioxidant genes was not examined. …
… Finally, the interaction between GST genes and other antioxidant genes was not examined. …
Biomarkers for the adverse effects on respiratory system health associated with atmospheric particulate matter exposure
C Guo, S Lv, Y Liu, Y Li - Journal of Hazardous Materials, 2022 - Elsevier
… MDA in urine, serum or EBC was frequently monitored to reflect air pollution-derived
systemic or airway oxidative stress. Quite a few studies have proven the elevated MDA level in …
systemic or airway oxidative stress. Quite a few studies have proven the elevated MDA level in …
Polymorphisms in oxidative stress, metabolic detoxification, and immune function genes, maternal exposure to ambient air pollution, and risk of preterm birth in …
N Zhao, W Wu, Y Feng, F Yang, T Han, M Guo… - Environmental …, 2021 - Elsevier
… the interactive effects of maternal air pollution and genetic … the thoracic region of the respiratory
system. There are serious risks to … unbalanced ROS, damaged antioxidant defenses, and …
system. There are serious risks to … unbalanced ROS, damaged antioxidant defenses, and …
Acute exposure to traffic-related air pollution alters antioxidant status in healthy adults
KE Cosselman, J Allen, KL Jansen, P Stapleton… - Environmental …, 2020 - Elsevier
… in antioxidant/stress response leukocyte gene expression (… significantly attenuated by the
selected antioxidant pre-treatment. … underlying the adverse effects of traffic-related air pollution. …
selected antioxidant pre-treatment. … underlying the adverse effects of traffic-related air pollution. …