… survival of patients with chronic myeloid leukemia (CML). Some … , in which treatment by TKI
was replaced by interferon‐α before … Chronic myeloid leukemia (CML) is associated with the …

… treatment with the highly effective CML therapeutics tyrosine kinase inhibitors (TKIs) and
interferon-α (… Chronic myeloid leukemia (CML) is a myeloid stem cell disease characterized by …

… Each myeloid malignancy is unique and therefore presents different challenges with regards
to treatment. MPNs have been categorized by the WHO as: chronic myeloid leukaemia (…

… or spanning the breakpoint confer an adverse prognosis to patients treated with interferon-α
(IFN-α) and second-line imatinib, but not to patients on frontline TKI therapy [[24], [25], [26], […

… Chronic myeloid leukemia patients in prolonged remission following interferon-α monotherapy
have distinct cytokine and oligoclonal lymphocyte profile. PLoS One 2011; 6: e23022. …

… Even in the era of ABL tyrosine kinase inhibitors, eradication of chronic myeloid leukemia
(CML… complete cure of the disease. Interferon-α (IFN-α) has long been used for the treatment of …

Abstract CML therapy has improved dramatically with the development of tyrosine kinase
inhibitors (TKIs). Prior to the TKI era, we conducted two trials of alpha-interferon (IFN) for post-…

… Although t(8;21) acute myeloid leukemia (AML) is considered to have a good prognosis,
relapse occurs in up to 50% of patients treated with chemotherapy, and the long‐term survival is …

… Furthermore, previous standards-of-care, including interferon-α, hold promise in attaining
TFR in the post-TKI era. A deeper understanding of the immunological landscape in CML is …

… Both pegylated interferon-α and standard interferon-α have been used safely during
pregnancy, although the data are from women with essential thrombocytosis. Hydroxycarbamide (…