Chronic myeloid leukemia harboring T315I and F317L mutations successfully treated with interferon-α and ponatinib

Y Motomura, K Arai, K Yoshifuji… - [Rinsho Ketsueki] The …, 2019 - europepmc.org
… Our patient was diagnosed with chronic myeloid leukemia (CML) in chronic phase (CP)
when he was 40 years old. Although dasatinib (DAS) was prescribed during his clinical course, …

Low‐dose tyrosine kinase inhibitors before treatment discontinuation do not impair treatment‐free remission in chronic myeloid leukemia patients: results of a …

E Cayssials, J Torregrosa‐Diaz, P Gallego‐Hernanz… - Cancer, 2020 - Wiley Online Library
therapy. Results appear independent of both dose reduction and potential pretreatment with
interferon-α… of chronic myeloid leukemia (CML). Currently, the life expectancy of patients in …

DC generation from peripheral blood mononuclear cells in patients with chronic myeloid leukemia: Influence of interferons on DC yield and functional properties

A Flörcken, J Kopp, U Kölsch, C Meisel… - Human Vaccines & …, 2016 - Taylor & Francis
Chronic myeloid leukemia is a clonal myeloproliferative disorder in which the characteristic
reciprocal translocation, t(9;22)(q34;q11) forms the Philadelphia chromosome and leads to …

Chronic myeloid leukemia with complex karyotypes: Prognosis and therapeutic approaches

AA Asnafi, Z Deris Zayeri, S Shahrabi… - Journal of cellular …, 2019 - Wiley Online Library
Chronic myeloid leukemia (CML) is a neoplastic disease … important roles in prognosis and
treatment strategies. Philadelphia (Ph… CML: chronic myeloid leukemia; INF-α: interferon-α; TKI: …

Assessment of imatinib as first-line treatment of chronic myeloid leukemia: 10-year survival results of the randomized CML study IV and impact of non-CML …

R Hehlmann, M Lauseker, S Saußele, M Pfirrmann… - Leukemia, 2017 - nature.com
… 400mg daily: results of SWOG S0325, an intergroup randomized PHASE II trial in newly
diagnosed chronic phase chronic myeloid leukaemia. Br J Haematol 2014; 164: 223–232. …

Chronic myeloid leukemia: Immunobiology and novel immunotherapeutic approaches

E Cayssials, F Guilhot - BioDrugs, 2017 - Springer
… Imatinib has revolutionized the treatment and prognosis of chronic myeloid leukemia (CML)
with survival rates now approaching those of the age-matched healthy population. To be …

Chronic myeloid leukemia developing after successful treatment of acute promyelocytic leukemia

F Huang, J Chang, C Du, R Tao - Indian Journal of Hematology and Blood …, 2016 - Springer
… (CML) that developed after successful treatment of … therapy with hydroxyurea, interferon-α
and arsenic trioxide. We propose that optimization of chemotherapy regimen and treatment

Pharmacotherapeutic advances for chronic myelogenous leukemia: beyond tyrosine kinase inhibitors

A Costa, E Scalzulli, I Carmosino, C Ielo… - Expert Opinion on …, 2024 - Taylor & Francis
… Immunotherapy with interferon-α (IFN-α) shows some biological effects, although further
research is needed for optimal application in enhancing discontinuation rates. Other …

A systematic literature review of the economic evaluations of treatments for patients with chronic myeloid leukemia

R Agrawal, J Vieira, J Ryan, H Negi, T Rajput… - …, 2022 - Springer
chronic phase chronic myeloid leukemia. Most models had a Markov structure, a 1 year to
lifetime time horizon, and a 1-month cycle length. Commonly assessed treatmentsinterferon-α

The effectiveness of interferon-α combined with imatinib in patient with chronic myeloid leukemia harboring T315I BCR-ABL1 mutation

H Zhang, Z Liang, Y Hu, X Wang, B Wang… - Leukemia & …, 2018 - Taylor & Francis
Chronic myeloid leukemia (CML) is a clonal disorder of multipotent hematopoietic progenitor
cells and is characterized by t (9; 22) (q34; q11) that produce the BCR-ABL fusion protein …