… efficacy of single-agent aerosol IL-2 and combination therapy aerosol IL-2 and NK cells or
aerosol IL-2 and interleukin 11 … therapy trials using this less invasive and less toxic approach. …

… We hypothesized that further immunostimulation with intravesical interleukin-2 and
subcutaneous granulocyte-macrophage colony-stimulating factor may improve response to …

… In conclusion, this prospective phase II single-arm trial showed that SAbR did not improve
the ORR of HD IL2 alone in mRCC patients, but also did not appear to increase toxicities. …

… In conclusion, we demonstrated high antitumour efficacy of combined IL-2 and IL-12 gene
… Interleukin 12 (IL-12), with its potent proinflammatory functions, is a suitable candidate for …

… Phase I evaluation of intravenous recombinant human interleukin 12 in patients with … Phase
I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer …

Invasive fungal infections cause approximately 1.5 million deaths per year worldwide and
are a growing threat to human health. Current anti-fungal therapies are often insufficient, …

… fever-range hyperthermia induced by interleukin-2 for 5 days. She went into complete
remission of her pulmonary metastases with transient WHO I-II diarrhea and skin rash. The patient …

… infections, malignancy or cardiovascular events from therapeutic modulation of the interleukin-13
pathway alone or the combined interleukin-13/… infections, invasive fungal infection or …

… , not only as single therapy, but also in combination with … as a single treatment or in
combination with other therapeutic … to cytokines such as interleukin-2 (IL-2) and interferon-γ (IFNγ…

… Expected impact on the infection risk Eosinophilia is a distinctive feature of some parasitic
infections, particularly those produced by tissue-invasive helminths (such as Schistosoma spp.…