Interleukin-15 in autoimmunity

H Allard-Chamard, HK Mishra, M Nandi, M Mayhue… - Cytokine, 2020 - Elsevier
… IL-15 signaling in autoimmunity. Unlike therapies targeting other … of IL-15 signaling in
autoimmunity and explore potential … role of IL-15 in autoimmune diseases and the complexities of …

[HTML][HTML] Interleukin-15 (dys) regulation of lymphoid homeostasis: Implications for therapy of autoimmunity and cancer

TA Waldmann, MD Miljkovic, KC Conlon - Journal of Experimental …, 2020 - rupress.org
IL-15, a pleiotropic cytokine, stimulates generation of NK, NK-T, γδ, ILC1, and memory CD8
T cells. IL-15 disorders play pathogenetic roles in organ-specific autoimmune diseases …

Interleukin‐6 and interleukin15 as possible biomarkers of the risk of autoimmune diabetes development

K Siewko, R Maciulewski… - BioMed Research …, 2019 - Wiley Online Library
… was to assay circulating interleukin-15 (IL-15) and interleukin-6 (IL-6) levels and insulin
resistance measured by two different methods in newly diagnosed autoimmune diabetes (AD) …

Interleukin 15: A key cytokine for immunotherapy

M Patidar, N Yadav, SK Dalai - Cytokine & growth factor reviews, 2016 - Elsevier
… IL-15 therapy is useful for controlling the experimental autoimmune … IL-15 greatly influences
autoimmune diseases, inflammatory disorders, … Novel human interleukin-15 agonists …

Trans-presentation of interleukin-15 by interleukin-15 receptor alpha is dispensable for the pathogenesis of autoimmune type 1 diabetes

D Bobbala, M Mayhue, A Menendez… - Cellular & molecular …, 2017 - nature.com
… Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage
of … Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the …

Interleukin-15 enhances proinflammatory T-cell responses in patients with MS and EAE

C Laurent, G Deblois, ML Clénet… - Neurology …, 2020 - AAN Enterprises
… We posit that interleukin-15 (IL-15) is a relevant contributor to MS … Interleukin-15 (IL-15)
is a potential contributing factor to the … in experimental autoimmune encephalomyelitis (EAE). …

Therapeutic potential of interleukin15 in cancer

G Isvoranu, M Surcel… - Experimental and …, 2021 - spandidos-publications.com
… , being involved in the pathogenesis of several autoimmune diseases. IL-15 induces … IL-15
has been detected in patients with such autoimmune diseases as inflammatory bowel …

Interleukin-15 as a potential new target in Sjögren's syndrome-associated inflammation

M Sisto, L Lorusso, S Lisi - Pathology, 2016 - Elsevier
… the discovery of pro-inflammatory cytokines accumulation in functionally and structurally
damaged areas of the salivary glands and its pathogenic significance in this autoimmune

Interleukin-15 as a biomarker candidate of rheumatoid arthritis development

W Kurowska, M Przygodzka, M Jakubaszek… - Journal of clinical …, 2020 - mdpi.com
interleukin-15 (IL-15) can serve as a new biomarker of RA development in patients with
undifferentiated arthritis (UA). Interleukin-15, … Interleukin-15 showed higher sensitivity (77.8%) …

[HTML][HTML] Elevated serum levels of interleukin-15 in pemphigus Vulgaris patients: A potential therapeutic target

M Kheirodin, Z Tehranchinia, Y Ketabi… - Dermatology Practical …, 2022 - ncbi.nlm.nih.gov
… (PV) is a rare autoimmune disease that causes painful blistering. Interleukin-15 (IL-15) as a
… with the development of the chronic inflammatory or autoimmune disease. There is not much …