… Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus Histoplasma
capsulatum… activity through a calcium-dependent mechanism of yeast permeabilization and…

… Chloroquine’s effects were both time- and dose-dependent and impacted fungal burden …
extracellular vesicles is a promising potential approach to modifying the virulence of the fungus. …

… capsulatum yeast cells enable them to parasitize phagocytic … attenuated virulence, and this
attenuation is dependent on the … intracellular catalase (CatP) further reduced yeast virulence …

… in the parasitic yeast form and promote production of virulence factors… and virulence have
been identified in Histoplasma. … A second strategy for iron uptake is dependent on extracellular …

… by yeast differentiation as well as environment-dependent … of intracellular Sod1, is required
for survival of Histoplasma … of Ggt1 does not impair Histoplasma yeast virulence in vivo, at …

… The fungal pathogen Histoplasma capsulatum infects tens to … is ultimately dependent on the
balance of Histoplasma virulence … a permissive intracellular environment, Histoplasma yeast …

… Histoplasma capsulatum (Hc) is a fungal intracellular … abundant virulence factor secreted by
Hc yeast cells is Calcium Binding … infection, we hypothesized that Cbp1-dependent virulence …

… the intracellular fungal pathogen Histoplasma capsulatum (… and display severely reduced
virulence in the mouse model of … Moreover, we show that CHOP-dependent macrophage lysis …

… Histoplasma capsulatum is a dimorphic fungal pathogen that … for full virulence, indicating the
Histoplasma containing … have attenuated virulence, and this attenuation is dependent on the …

… capsulatum yeast cells enable them to parasitize phagocytic … relies on the anaerobic
metabolism since ADH is a Zn-dependent … meaning of this cell surface morphology in virulence of …