[HTML][HTML] Molecular mechanisms of Porphyromonas gingivalis-host cell interaction on periodontal diseases

M Nakayama, N Ohara - Japanese Dental Science Review, 2017 - Elsevier
gingivalis induces cellular signaling alteration in host cells. Phosphatidylinositol 3-kinase
(… Fimbriae are a pivotal factor to adhere to host cell surface, extracellular matrix proteins, and …

Porphyromonas gingivalis activates NFκB and MAPK pathways in human oral epithelial cells

S Groeger, F Jarzina, E Domann, J Meyle - BMC immunology, 2017 - Springer
… HMGB1 is released into the extracellular area after stimulation … (CARD) interaction with
receptor-interacting protein kinase … 1 to induce the expression of the IL-1 family cytokine IL-36 …

Porphyromonas gingivalis: Immune Subversion Activities and Role in Periodontal Dysbiosis

G Hajishengallis, PI Diaz - Current oral health reports, 2020 - Springer
… by which Porphyromonas gingivalis interacts with community … gingivalis has been shown
to induce cell death and DNA … the production of inflammatory cytokines. Contrary to MYD88, …

Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
… One example of direct interaction is that P. … TLR2 and induce the production of pro-inflammatory
cytokines, such … /macrophages, resulting in extracellular signal-regulated kinase 1/2 (…

[HTML][HTML] Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors

L Jia, N Han, J Du, L Guo, Z Luo, Y Liu - Frontiers in cellular and …, 2019 - frontiersin.org
… receptors, the intracellular signal transmission pathways are … immune response, induces
inflammation and cytokine production, … the vital function of mediating the interaction between P. …

The role of toll‐like and protease‐activated receptors and associated intracellular signaling in Porphyromonas gingivalis‐infected gingival fibroblasts

E Palm, I Demirel, T Bengtsson, H Khalaf - Apmis, 2017 - Wiley Online Library
… expression after PAR1 silencing in Porphyromonas gingivalis-… pathogen–host interactions,
and the signaling pathways utilized … Our results suggest that induction of CXCL8 and IL-6 is …

Porphyromonas gingivalis adopts intricate and unique molecular mechanisms to survive and persist within the host: a critical update

A Chopra, SG Bhat, K Sivaraman - Journal of Oral Microbiology, 2020 - Taylor & Francis
interaction activates a cascade of signaling pathways that cause release of proinflammatory
cytokines … and decrease the release of cytokine-induced neutrophil chemoattractant (CINC) …

Immunological Pathways Triggered by Porphyromonas gingivalis and Fusobacterium nucleatum: Therapeutic Possibilities?

KQ De Andrade, CLC Almeida-da-Silva… - Mediators of …, 2019 - Wiley Online Library
… Here, we review innate and adaptive immune responses induced by P. … interactions with
the host. We discuss the role of TLRs, the inflammasome, purinergic signaling, cytokines, and …

Porphyromonas gingivalis lipopolysaccharide induces pro-inflammatory adipokine secretion and oxidative stress by regulating Toll-like receptor-mediated signaling …

F Le Sage, O Meilhac, MP Gonthier - Molecular and cellular endocrinology, 2017 - Elsevier
interaction of LPS with TLR4 due to an adaptive immune response to TLR2 blocking, leading
to an increased induction of IL-6 … recruitment of additional intracellular signaling molecules. …

[HTML][HTML] Proinflammatory signaling cascades of periodontopathic oral pathogen porphyromonas gingivalis

BL Slomiany, A Slomiany - Journal of Biosciences and Medicines, 2018 - scirp.org
… has been implicated in the interaction with proinflammatory cytokines to control local …
interaction with Syk, we found that stimulation with the LPS led to a rapid, time-dependent induction