Intracranial meningiomas decrease in volume on magnetic resonance imaging after discontinuing progestin

EHJ Voormolen, PO Champagne, E Roca… - …, 2021 - journals.lww.com
OBJECTIVE To investigate the relationship between growth kinetics of intracranial
meningiomas and usage of the progestin cyproterone acetate (PCA). METHODS This study
prospectively followed 108 women with 262 intracranial meningiomas and documented
PCA use. A per-meningioma analysis was conducted. Changes in meningioma volumes
over time, and meningioma growth velocities, were measured on magnetic resonance
imaging (MRI) after stopping PCA treatment. RESULTS Mean follow-up time was 30 …
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