Glaucoma is extensively treated with topical eye drops containing drugs. However, the
retention time of the loaded drugs and the in vivo bioavailability of the drugs are highly
influenced before reaching the targeted area sufficiently, due to physiological and
anatomical barriers of the eye, such as rapid nasolacrimal drainage. Poor intraocular
penetration and frequent administration may also cause ocular cytotoxicity. A novel
approach to overcome these drawbacks is the use of injectable hydrogels administered …

Glaucoma is extensively treated with topical eye drops containing drugs. However, the
retention time of the loaded drugs and the in vivo bioavailability of the drugs are highly
influenced before reaching the targeted area sufficiently, due to physiological and
anatomical barriers of the eye, such as rapid nasolacrimal drainage. Poor intraocular
penetration and frequent administration may also cause ocular cytotoxicity. A novel
approach to overcome these drawbacks is the use of injectable hydrogels administered …