Recent advances in gossypol derivatives and analogs: a chemistry and biology view
Y Lu, J Li, CE Dong, J Huang, HB Zhou… - Future Medicinal …, 2017 - Taylor & Francis
… From all of the molecules described in this review based on almost 30 years of research,
only (-)-gossypol (AT-101) was under clinic trial but with unsatisfied cytotoxicity. Therefore, in …
only (-)-gossypol (AT-101) was under clinic trial but with unsatisfied cytotoxicity. Therefore, in …
The potential roles of gossypol as anticancer agent: advances and future directions
D Paunovic, J Rajkovic, R Novakovic… - Chinese Medicine, 2023 - Springer
… is available on the drug market as an adjuvant used for tumour treatment [85], in the rest of
the world, gossypol is still under clinical trials investigation. This comprehensive study aims to …
the world, gossypol is still under clinical trials investigation. This comprehensive study aims to …
Gossypol and its natural derivatives: multitargeted phytochemicals as potential drug candidates for oncologic diseases
… The intent for this review is to describe recent advances in the chemotherapeutic potential of
… -depth analysis of current research as presented in this review, gossypol-derived bioactive …
… -depth analysis of current research as presented in this review, gossypol-derived bioactive …
Feasibility study on the use of near-infrared spectroscopy for rapid and nondestructive determination of gossypol content in intact cottonseeds
C Li, B Su, T Zhao, C Li, J Chen, S Zhu - Journal of Cotton Research, 2021 - Springer
… In this present study, spectroscopy has investigated the feasibility of analyzing gossypol in
… at room temperature, three samples were randomly employed to determine the changes of …
… at room temperature, three samples were randomly employed to determine the changes of …
Natural product gossypol and its derivatives in precision cancer medicine
… Our group has investigated the extraction and resolution of gossypol, the synthesis of its …
To solve this problem, the development of nanocarriers in drug delivery expanded our …
To solve this problem, the development of nanocarriers in drug delivery expanded our …
Evaluation of ozone technology as an alternative for degradation of free gossypol in cottonseed meal: a prospective study
AC Romero, MA Calori-Domingues… - Food Additives & …, 2021 - Taylor & Francis
… was virtually eliminated after 15 minutes of exposure to ozone when the gas found conditions
to readily react with gossypol molecule (in the present work, in the model system of glass …
to readily react with gossypol molecule (in the present work, in the model system of glass …
Systematic review of Gossypol/AT-101 in cancer clinical trials
O Renner, M Mayer, C Leischner, M Burkard, A Berger… - Pharmaceuticals, 2022 - mdpi.com
… gossypol/AT-101 application within clinical investigations and focus on clinical outcomes,
dose-limiting toxicities, and the relation of gossypol/… Finally, we summarize the current data of …
dose-limiting toxicities, and the relation of gossypol/… Finally, we summarize the current data of …
Recent advances and future perspectives in cotton research
G Huang, JQ Huang, XY Chen… - Annual review of plant …, 2021 - annualreviews.org
… , and epigenetic modifications, are involved in fiber development. Finally, we describe the
involvement of the gossypol biosynthetic pathway in the manipulation of herbivorous insects, …
involvement of the gossypol biosynthetic pathway in the manipulation of herbivorous insects, …