Involvement of the monoaminergic system in the antidepressant-like effect of the crude extract of Mentha piperita (Lamiaceae) in the forced swimming test in mice

S Abbasi-Maleki, A Bakhtiarian, V Nikoui - Synergy, 2017 - Elsevier
The aim of the present study was to investigate the involvement of the monoaminergic
system in antidepressant-like effects of a characterized ethanolic extract of Mentha piperita
(MP) in the forced swimming test (FST) in male mice. The animals were intraperitoneally (ip)
treated with the MP extract (50–400 mg/kg) one hour before FST. To examine the
involvement of the monoaminergic system in the antidepressant-like effect of MP, receptor
antagonists were administrated fifteen minutes prior to the MP extract treatment (400 mg/kg …
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