Assessment of culture/preservation conditions of human islets for transplantation
Y Shindo, J Kalivarathan, PB Saravanan… - … Transplantation, 2022 - journals.sagepub.com
… or preservation of islets before transplantation is required to … effect of islet preservation on
viability and function of islets when … to identify optimal culture/preservation conditions that result …
viability and function of islets when … to identify optimal culture/preservation conditions that result …
Optimal Time to Ship Human Islets Post Tissue Culture to Maximize Islet Recovery
BJ Olack, M Alexander, CJ Swanson… - … Transplantation, 2020 - journals.sagepub.com
… In summary, we determined that an increased duration of 37C culture time for human islets
prior to overnight shipping may reduce islet loss experienced by investigator recipients. This …
prior to overnight shipping may reduce islet loss experienced by investigator recipients. This …
Advances in pancreatic islet transplantation sites for the treatment of diabetes
F Cayabyab, LR Nih, E Yoshihara - Frontiers in endocrinology, 2021 - frontiersin.org
… days before the islet develops a functional vasculature (111), but even then, the transplanted
islets … In addition, islets transplanted in the epidermal fat site have lower, controlled glucose …
islets … In addition, islets transplanted in the epidermal fat site have lower, controlled glucose …
The journey of islet cell transplantation and future development
A Gamble, AR Pepper, A Bruni, AMJ Shapiro - Islets, 2018 - Taylor & Francis
… of islet cell transplantation, limitations associated with this procedure and methods to alleviate
islet … Before transplantation, the purified islet preparation must undergo detailed quality …
islet … Before transplantation, the purified islet preparation must undergo detailed quality …
Human serum versus human serum albumin supplementation in human islet pretransplantation culture: in vitro and in vivo assessment
M Nacher, E Estil· Les, A Garcia, B Nadal… - … Transplantation, 2016 - journals.sagepub.com
… -and HSA-cultured islets transplanted into the anterior chamber … islets and improve the
outcome of islet transplantation. … supplement human islet culture before transplantation. However, …
outcome of islet transplantation. … supplement human islet culture before transplantation. However, …
National Institutes of Health–sponsored Clinical Islet Transplantation Consortium phase 3 trial: manufacture of a complex cellular product at eight processing facilities
C Ricordi, JS Goldstein, AN Balamurugan, GL Szot… - Diabetes, 2016 - Am Diabetes Assoc
… islet transplantation (1–4). In 2000, the University of Alberta reported that transplantation of
allogeneic purified islet … Purified islets were cultured for 36–72 h before transplantation. For …
allogeneic purified islet … Purified islets were cultured for 36–72 h before transplantation. For …
[HTML][HTML] Human islet isolation and distribution efforts for clinical and basic research
N Ng, WX Tan, Y Koh, A Teo - OBM Transplantation, 2019 - lidsen.com
… This review also highlights the value of human islets for clinical transplantation as well as
basic … Functional validation prior to clinical islet transplantation is presently not mandatory, but …
basic … Functional validation prior to clinical islet transplantation is presently not mandatory, but …
Semi-automated assessment of human islet viability predicts transplantation outcomes in a diabetic mouse model
M Salgado, N Gonzalez, L Medrano… - … transplantation, 2020 - journals.sagepub.com
… , Aliso Viejo, CA, USA) until they were distributed for analyses. … of isolated islets: islet
count (post-isolation islet equivalent … use of clinical islet transplantation data, before it can be …
count (post-isolation islet equivalent … use of clinical islet transplantation data, before it can be …
Modified cell-permeable JNK inhibitors efficiently prevents islet apoptosis and improves the outcome of islet transplantation
H Noguchi, C Miyagi-Shiohira, Y Nakashima, N Ebi… - Scientific reports, 2018 - nature.com
… that was transduced into the isolated islets. Our data showed that treatment with 8R-sJNKI(-9)
before islet transplantation led to improved islet function at one tenth the concentration of …
before islet transplantation led to improved islet function at one tenth the concentration of …
The future of clinical islet transplantation in the United States
MF Knoll, CA Knoll, R Bottino, S Bertera… - OBM Transplantation, 2021 - lidsen.com
… been a world leader in autologous islet transplantation (Tx) (ie, … world in allogeneic islet Tx
(ie, islets from deceased human … for islet xenoTx remains problematic until allogeneic islet Tx …
(ie, islets from deceased human … for islet xenoTx remains problematic until allogeneic islet Tx …
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