[HTML][HTML] Loss of PRC2 subunits primes lineage choice during exit of pluripotency
CH Loh, S van Genesen, M Perino, MR Bark… - Nature …, 2021 - nature.com
… MTF2 and JARID2 in embryonic stem cells (ESCs). In this … Mtf2 and Jarid2 mutants further
revealed the requirement for … Mtf2 null cells exhibit multi-lineage derepression of gene …
revealed the requirement for … Mtf2 null cells exhibit multi-lineage derepression of gene …
[HTML][HTML] Cell signaling coordinates global PRC2 recruitment and developmental gene expression in murine embryonic stem cells
… required for multi-lineage differentiation and recruitment of … by reduced expression of PRC2
components, we performed … expression of PRC2-recruiting factor JARID2 was significantly …
components, we performed … expression of PRC2-recruiting factor JARID2 was significantly …
A novel form of JARID2 is required for differentiation in lineage‐committed cells
D Al‐Raawi, R Jones, S Wijesinghe, J Halsall… - The EMBO …, 2019 - embopress.org
… (2010) Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage
differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. Nat …
differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. Nat …
Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells
HG Asenjo, A Gallardo, L López-Onieva, I Tejada… - Science …, 2020 - science.org
… across cell cycle in mouse embryonic stem cells (mESCs). … the lack of the PRC2-recruiter
Jarid2 affected the cell cycle–… Additional data related to this paper may be requested from …
Jarid2 affected the cell cycle–… Additional data related to this paper may be requested from …
[HTML][HTML] The complexity of PRC2 subcomplexes
… de novo recruitment of PRC2 is required to maintain Polycomb … of human PRC2 with its
cofactors AEBP2 and JARID2. … We mainly focus on PRC2 in mouse embryonic stem cells (mESCs…
cofactors AEBP2 and JARID2. … We mainly focus on PRC2 in mouse embryonic stem cells (mESCs…
[HTML][HTML] LncRNAs and PRC2: coupled partners in embryonic stem cells
… These accessory proteins, also required for a proper … of JARID2, the interaction between
Meg3 and PRC2 is much … PRC2 is recruited to the Hoxa locus and is part of a complex …
Meg3 and PRC2 is much … PRC2 is recruited to the Hoxa locus and is part of a complex …
Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal
A Ferreccio, J Mathieu, D Detraux, L Somasundaram… - Cell Cycle, 2018 - Taylor & Francis
… requirement in the 2iL-IF state [Citation20]. We show that while other PRC2 components are
expressed in both stages, JARID2 … ES cells, as evidenced by their impaired differentiation in …
expressed in both stages, JARID2 … ES cells, as evidenced by their impaired differentiation in …
[HTML][HTML] JARID2 and the PRC2 complex regulate the cell cycle in skeletal muscle
A Adhikari, P Mainali, JK Davie - Journal of Biological Chemistry, 2019 - ASBMB
… Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage
differentiation and recruitment of PRC1 and RNA polymerase II to developmental regulators. …
differentiation and recruitment of PRC1 and RNA polymerase II to developmental regulators. …
[HTML][HTML] Two functional axes of feedback-enforced PRC2 recruitment in mouse embryonic stem cells
M Perino, G van Mierlo, C Loh, SMT Wardle… - Stem Cell Reports, 2020 - cell.com
… Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation
… established by JARID2, MTF2, and H3K27me3. Our data provide further evidence on the …
… established by JARID2, MTF2, and H3K27me3. Our data provide further evidence on the …
[HTML][HTML] Late-stage differentiation of embryonic pancreatic β-cells requires Jarid2
S Cervantes, M Fontcuberta-PiSunyer, JM Servitja… - Scientific Reports, 2017 - nature.com
… H3K27me3 deposition, in embryonic stem cells. However, … that Jarid2 is required in progenitor
cells to activate the β-cell … of PRC2 components and, specifically, expression of Jarid2, is …
cells to activate the β-cell … of PRC2 components and, specifically, expression of Jarid2, is …