Unique structural platforms of Suz12 dictate distinct classes of PRC2 for chromatin binding
… Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage
differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. …
differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. …
Capturing the onset of PRC2-mediated repressive domain formation
… First, PRC2 is stably recruited by the actions of JARID2 and MTF2 to a limited number of …
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation …
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation …
Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2
S Cooper, A Grijzenhout, E Underwood… - Nature …, 2016 - nature.com
… RYBP, a core component of non-canonical PRC1 previously … that H2AK119u1 is
required to initiate PRC2 recruitment by … enrichment on Xi in differentiating XX ES cells (unpublished). …
required to initiate PRC2 recruitment by … enrichment on Xi in differentiating XX ES cells (unpublished). …
[PDF][PDF] Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by
Y Yu, P Deng, B Yu - Stem cell reports, 9 (3), 2017 - scholar.archive.org
… that does not fulfill the requirements of tissue regeneration. Mesoderm … JARID2 are both
components of PRC2, we investigated the gene expression of each individual PRC2 component. …
components of PRC2, we investigated the gene expression of each individual PRC2 component. …
Polycomb repressive complex (es) and their role in adult stem cells
… In embryonic stem (ES) cells, PcG proteins play an … and JARID2 in PRC2.2 complexes
allosterically stimulates PRC2 … function is required to suppress adipogenic differentiation in …
allosterically stimulates PRC2 … function is required to suppress adipogenic differentiation in …
[图书][B] The Epigenetic Mechanisms of Polycomb and Trithorax Proteins in Stem Cell Maintenance and Leukemogenesis
M Aljazi - 2022 - search.proquest.com
… genes critical for mouse embryonic stem cell (mESC) … reduced occupancy for Jarid2
and PRC2 and decreased … PRC2 mediating H3K27me3, is required during mesodermal …
and PRC2 and decreased … PRC2 mediating H3K27me3, is required during mesodermal …
JARID2 functions as a tumor suppressor in myeloid neoplasms by repressing self-renewal in hematopoietic progenitor cells
… of chronic myeloid diseases is required for the development of targeted … Mechanistically,
JARID2 recruits PRC2 to gene bodies to … -KO Vav HSCs were unable to sustain multi-lineage …
JARID2 recruits PRC2 to gene bodies to … -KO Vav HSCs were unable to sustain multi-lineage …
Posttranscriptional (re) programming of cell fate: examples in stem cells, progenitor, and differentiated cells
C Kanellopoulou, SA Muljo - Frontiers in immunology, 2018 - frontiersin.org
… ) axis plays a role in setting the chromatin landscape of embryonic stem cells (ESCs) to support
… of Jarid2, a target of miR-155 in Th17 cells (Figure 1B), and a key component of PRC2. It …
… of Jarid2, a target of miR-155 in Th17 cells (Figure 1B), and a key component of PRC2. It …
EPOP functionally links elongin and polycomb in pluripotent stem cells
… Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation
… associates with the PRC2 core components and PCL2, but not with JARID2 (Figure 1D). …
… associates with the PRC2 core components and PCL2, but not with JARID2 (Figure 1D). …
Autoregulation of JARID2 through PRC2 interaction with its antisense ncRNA
D Al-Raawi, A Kanhere - BMC Research Notes, 2020 - Springer
… are needed which can verify JARID2-AS1-PRC2 interactions. … Without JARID2, embryonic
stem cells cannot differentiate. … ncRNA overlapping PRC2 component JARID2 and presents an …
stem cells cannot differentiate. … ncRNA overlapping PRC2 component JARID2 and presents an …