… Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL):
analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) …

… of prognostic factors on 237 adult patients with B-ALL treated … significance of the potential
prognostic factors on OS and … prognostic factors had independently significant prognostic value …

… A total of 14 (3%) patients had ALL with TCF3-PBX1 detected by karyotyping (n = 10) and/or
FISH analysis (n = 10). Karyotyping, FISH and SNP array analysis revealed the unbalanced …

… karyotype, low hypodiploidy, and near-triploidy are independent adverse prognostic factors
in adult ALL… to the clinical impact of ploidy in adult ALL have been difficult to obtain because …

… monosomal karyotypes, had no prognostic value in these intensive protocols designed for …
have been established as independent prognostic factors, mainly in children. In adults, the t(9;…

… karyotyping from both adult and pediatric patients respectively [23,24,25]. However, two of
these reports have not evaluated the karyotyping data with other prognostic factors … ALL [25]. …

… events causing leukemia (Table 1).4, 31, 32, 33, 34 The disparity in outcomes of children
and adults with ALL is partially due to the incidence of favorable and unfavorable karyotypes. …

… Cytogenetic classifications were performed based on anticipated prognostic factors in this …
demonstrated the independent prognostic value of low hypodiploidy and complex karyotype in …

… prognostic factors in acute myeloid leukemia (AML) [Citation21] and in myelodysplastic
syndromes [Citation26]. In AML, MK is defined as any karyotype without core binding factor-…

… clinical impact irrespective of standard prognostic factors in patients with BCR-ABL negative
ALL. The remission rate of adult acute lymphoblastic leukemia (ALL) has risen substantially …