… Recent work demonstrated existence of a kinetic competition between Pol II elongation and
… , we reasoned that sites with Pol II readthrough should still roadblock DNA Pol δ. Indeed, we …

… transcribed polycistronically by RNA polymerase II (RNAPII). Little is known about transcription
termination … RNAPII kinetics There is a kinetic competition between RNAP II and the 5’ to 3…

… Most DNA in the genomes of higher organisms does not code for proteins. RNA Polymerase
II (Pol II) transcribes non-coding DNA into long non-coding RNAs (lncRNAs), but biological …

… -K363R is associated with transcription termination defects in vivo and reduced RNA binding
affinity in vitro… Unravelling the means to an end: RNA polymerase II transcription termination …

… termination, transcription of small non-coding RNAs including snRNAs and snoRNAs, are
terminated by the Nrd1, Nab3 and Sen1 dependent … a kinetic race between transcribing …

… subunit in RNA polymerase II CUT: cryptic unstable transcript … for RNAPII: the Nrd1-Nab3-Sen1
dependent pathway, the … constant, and the kinetic competition between Xrn2 and RNAPII …

… RNA polymerase II (RNAPII) transcription is crucial for gene expression. RNAPII density …
alters kinetic competition between transcriptional stalling, termination, and further elongation. …

… Single-cell quantification of transcription kinetics and variability promotes a mechanistic
understanding of gene regulation. Here, using single-molecule RNA fluorescence in situ …

… termination factors described above, RNA polymerase pausing is a strict requirement for
Sen1-dependent termination … for a kinetic competition between termination and RNAPII …

… the relationship between RNA Polymerase II (Pol II) activity, functions of Spt elongation
factors, and cryptic transcription because of the previous observation that increased-activity Pol II …