Nrd1p identifies aberrant and natural exosomal target messages during the nuclear mRNA surveillance in Saccharomyces cerevisiae

P Singh, A Chaudhuri, M Banerjea… - Nucleic Acids …, 2021 - academic.oup.com
transcription termination pathway operates, influencing the stability of a few protein-coding
transcripts … Decay kinetics of representative transcription-elongation-defective ACT1-Tad and …

A transcriptional roadblock protects yeast centromeres

S Hedouin, GA Logsdon, JG Underwood… - Nucleic Acids …, 2022 - academic.oup.com
… from early log phase cultures or from G1 arrest/release kinetics was extracted using TRIzol
(… T7 RNA polymerase was added to initiate transcription and the resulting RNA products were …

So close, no matter how far: multiple paths connecting transcription to mRNA translation in eukaryotes

B Slobodin, R Dikstein - EMBO reports, 2020 - embopress.org
RNA polymerase II … Interestingly, while AUG-starting uORFs tend to compete with the main
ORF, mRNAs … complex effect on translation: reducing the kinetics of codon–anti-codon pairing …

[图书][B] Transcription kinetics in pluripotent cells: RNA turnover, transcription velocity, and epigenomic regulation

R Shao - 2022 - search.proquest.com
… of transcription velocity to each annotated TU, by integration of RNA polymerase II (Pol II) …
After explaining transcription velocity with chromatin features, we also evaluated its genome-…

New factors involved in transcription-associated genome instability

JA Mérida-Cerro - 2019 - digital.csic.es
RNA polymerase II profile does not change in GAL1p:LYS2:Sμ350…..58 3.2.5. RNA
polymerase II … damages by two different and competing pathways: nonhomologous end joining (…

The role of the RNA 5'end cap in the regulation of gene expression

O Zanin - 2023 - etheses.bham.ac.uk
… to the 5’ end of the products of the RNA polymerase II. The m7G … In the Sen1-dependent
termination the set of proteins that … The kinetic competition between Rat1 and the Poll II for the …

The life of U6 small nuclear RNA, from cradle to grave

AL Didychuk, SE Butcher, DA Brow - Rna, 2018 - rnajournal.cshlp.org
… silenced for Pol II by an unknown mechanism coupled to Sen1-dependent termination of
an … The dynamic telestem and U6 ISL structures may help U6 molecules avoid kinetic or …

The Kinetics of RNA Flow Across Subcellular Compartments

BM Smalec - 2022 - search.proquest.com
… are synthesized by RNA polymerase II (pol II). The residence time of mRNAs on chromatin
is inherently linked to the kinetics of transcription. The amount of time required to transcribe a …

Survey of cryptic unstable transcripts in yeast

JM Vera, RD Dowell - BMC genomics, 2016 - Springer
… Cryptic unstable transcripts (CUTs) comprise a fraction of the unstable RNA population in …
-coding RNAs (ncRNAs) are RNA polymerase II transcribed and capped, but are terminated

An essential RNA-binding lysine residue in the Nab3 RRM domain undergoes mono and trimethylation

KY Lee, A Chopra, K Biggar, MD Meneghini - bioRxiv, 2019 - biorxiv.org
… Consistent with this hypothesis, K363R mutation decreases RNA binding of the Nab3 RRM
in vitro and causes transcription termination defects in vivo. These findings reveal crucial …