Modeling of degradation kinetics of Salvianolic acid B at different temperatures and pH values

X Gong, S Huang, J Pan, H Qu - Chinese Journal of Chemical Engineering, 2017 - Elsevier
… The degradation kinetics of Salvianolic acid B, lithospermic acid, and Danshensu in a
Salvia miltiorrhiza extract aqueous solution were predicted using the mechanism model. The …

Degradation Kinetics and Mechanism of Lithospermic Acid under Low Oxygen Condition Using Quantitative 1H NMR with HPLC-MS

J Pan, X Gong, H Qu - Plos one, 2016 - journals.plos.org
… the degradation kinetics of LA, not to mention the kinetics of LA transform to Sal A. A possible
reason was that Sal A was not stable in aqueous solutions and could be easily oxidized [4]. …

Effects of ultrasonic processing on degradation of salvianolic acid B in aqueous solution

YX Guo, L Zhang, L Lu, EH Liu, CZ Shi - Journal of Pharmaceutical and …, 2016 - Elsevier
degradation of Sal B followed first-order kinetics under ultrasonic power of 600 W in aqueous
solution… form isomers 2 and 3 of lithospermic acid in a mild acid solution. Isomers 2 and 3 of …

Advanced process control for salvianolic acid A conversion reaction based on data-driven and mechanism-driven model

X Dong, X Yan, H Qu - Process Biochemistry, 2022 - Elsevier
… It has been proved that the degradation of SAB mainly … followed by hydrolysis into lithospermic
acid isomer by losing … According to the transformation mechanism of SAB to SAA, a kinetic

Three-liquid-phase extraction and re-partition as an integrated process for simultaneous extraction and separation of lithospermic acid B and tanshinone IIA

Y Gou, X Mu, Y Li, M Tang, G Chen, S Xiao - Biochemical Engineering …, 2021 - Elsevier
… Moreover, degradation of LAB and Tan IIA could occur at high temperature [34], [35]. …
fractions for ethanol and aqueous solution NaH 2 PO 4 (pH 2.55, 3.75 mol/L) was set as 76.0%. …

Superior stability of hydroxysafflor yellow a in xuebijing injection and the associated mechanism

W Pu, H Zhang, M Wang, Y Liu, L Sun, X Ren - Molecules, 2017 - mdpi.com
… The parameters associated with the degradation kinetics of HSYA in aqueous solution and
XBJ under … We found that HSYA was liable to degradation in aqueous solution under alkaline …

Rapid quantitation and identification of the chemical constituents in Danhong Injection by liquid chromatography coupled with orbitrap mass spectrometry

L Xu, Z Shang, T Bo, L Sun, Q Guo, X Qiao… - … of Chromatography A, 2019 - Elsevier
acid A (A2) by comparing with a reference standard. P45 was identified as lithospermic acid.
… The degradation and conversion of phenolic acids may be a key factor compromising the …

Phenylboronic Acid and Amino Bifunctional Modified Adsorbent for Quickly Separating Phenolic Acids from Crude Extract of Clerodendranthus spicatus and …

M Cheng, Q Song, X Zhang, P Zheng, R Zhao, Y Li… - Molecules, 2023 - mdpi.com
… , presumably due to phenylboronic acid degradation. A weight loss of 5.54… kinetics, 20 mg
of SiO 2 -NH 2 -FPBA was added into 20 mL of 0.5 mg/mL aqueous solution of phenolic acids

Effective adsorption of salvianolic acids with phenylboronic acid functionalized polyethyleneimine-intercalated montmorillonite

J Su, J Qian, W Zeng, Y Wang, G Kai - Separation and Purification …, 2023 - Elsevier
… The mobile phases included 0.1 % formic acid aqueous solution acetonitrile. The flow rate of
… amount, implying that the more content of phenylboronic acid, the slower adsorption kinetic. …

Analysis of Pharmaceutical Processes in Chinese Medicine Based on Quantity and Measure Value Transfer: A Case of Salvia miltiorrhiza Purified Extract Preparation

J Qian, Y Chen, Y Tai, Z Tang, Z Wang, K Guo, X Liu… - Separations, 2023 - mdpi.com
… the hydrolysis of lithospermic acid and salvianolic acid B to … degrade easily. The thermal
hydrolysis process significantly decreased the purity of lithospermic acid and salvianolic acid B. …