… the apolipoprotein E polymorphism and the kringle-IV repeat polymorphism of the LPA
gene … the commonly assumed inverse relationship between apo(a) isoform size and Lp(a) …

… under strict genetic control by the LPA gene locus and here especially by a size polymorphism
of apo(a) caused by a variable number of kringle IV (KIV) repeats in the LPA gene [1, 6]. …

… the role of LPA gene KIV-2 size polymorphism and single nucleotide polymorphisms (SNPs)
(… Our major finding is that low LPA KIV-2 repeat number is significantly and independently …

… and LPA Kringle IV type 2 (KIV-2) size polymorphism in … between Lp(a) plasma levels, LPA
KIV-2 size polymorphism, reflecting a variable number of kringle (K) IV type 2 apolipoprotein (…

… by polymorphisms in the LPA gene coding for apolipoprotein(a). The kringle IV type 2 (KIV-2)
repeat polymorphism is particularly important; it determines apolipoprotein(a) size that …

… (a), LPA kringle-IV type 2 (KIV-2) number of repeats, and LPA … , the kringle IV-2 repeats, which
give rise to size heterogeneity… quantitation of apo(a) independent of its size polymorphism. …

… The LPA gene codes for apo(a) whose genetic heterogeneity … between apoB 100 in LDL
and kringle IV in apo(a) [44]. The … inverse relationship between apo(a) size polymorphism and …

… of varying size, apolipoprotein(a), covalently bound. … variation in the apolipoprotein(a)-coding
LPA gene, may vary … in 70 286, LPA kringle-IV type 2 (KIV-2) number of repeats genotype …

… apolipoprotein(a) that included 455 patients. Common … low number of Kringle IV type 2 (KIV
2 ) repeats, which translate … , mainly represented by single nucleotide polymorphisms (snps) …

… multiallelic copy number variation in the LPA gene and the strong association with coronary
… of the Lp(a)/LPA trait, as well as aspects of genetic epidemiology. It highlights the role of …