[HTML][HTML] Methylation status of the adeno-associated virus type 2 (AAV2)

R Tóth, I Mészáros, D Hüser, B Forró, S Marton, F Olasz… - Viruses, 2019 - mdpi.com
… In the absence of a helper virus, they can establish a latent … During the first months,
recombinant AAV-mediated gene … an access of the host immune system to immunostimulatory, …

Combinatorial antigen targeting: ideal T-cell sensing and anti-tumor response

M Themeli, M Sadelain - Trends in molecular medicine, 2016 - cell.com
… the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated
transgene expression in … of recombinant adeno-associated virus. …

Multidimensional control of therapeutic human cell function with synthetic gene circuits

HS Li, DV Israni, KA Gagnon, KA Gan, MH Raymond… - Science, 2022 - science.org
… Overall, we lack versatile, scalable, and clinically viable gene circuit … regulatory system showed
multiyear functionality in nonhuman … Shown is the correlation of transcriptomes from RNA-…

[PDF][PDF] Pharmacologically controlled neurotrophic factor gene therapy for Parkinson's disease

S Cheng - 2019 - ediss.uni-goettingen.de
… occurring parvovirous, adeno-associated virus. The replication … suppressed, which prevented
transactivation of the gene in … By its low toxicity in long-term administration, mifepristone is …

[引用][C] Optimized AAV systems for the treatment of CNS-related diseases

M Marino - 2022

[PDF][PDF] Gene Therapy for Regenerative Medicine. Pharmaceutics 2023, 15, 856

H Hosseinkhani, AJ Domb, G Sharifzadeh, V Nahum - 2023 - pdfs.semanticscholar.org
… -AdV longevity via encoding novel tetracyclinedependent (TetOn)-… transactivation are
associated with their use [76,153]. Non-… the host immune response to adeno-associated virus

[HTML][HTML] A Clinically Viable Approach to Cell Programming

F Lin - 2023 - liebertpub.com
Immune responses against tetracycline-dependent transactivators affect long-term expression
of mouse erythropoietin delivered by a helper-dependent adenoviral vector. J Gene Med …

[PDF][PDF] The self-inactivating KamiCas9 system for the editing of CNS disease genes

N Merienne, G Vachey, L de Longprez, C Meunier… - Cell reports, 2017 - cell.com
Long-term immune or inflammatory responses due to … with 10 ng/mL recombinant human
FGF2. Cells are fed daily and … vectors o Production of adeno-associated vectors o Isolation and …

[图书][B] A Microfluidic Platform to Investigate the Mechanism by which GDNF Overexpression in Schwann Cells Causes Neuronal Axon Entrapment

ZZ Wang - 2019 - search.proquest.com
… and nerve compression in longterm implantation. Therefore, … immune response to the
foreign transactivator in rodents and … In particular, the use of adeno-associated and lenti-viral

Ligify: Automated genome mining for ligand-inducible transcription factors

S d'Oelsnitz, AD Ellington, D Ross - bioRxiv, 2024 - biorxiv.org
… non-model bacterium1 to monkeys2. While early applications … as inducer molecules, since
they are generally difficult to … One of the largest failure modes was caused by the lack of a …