Letermovir prophylaxis for cytomegalovirus in hematopoietic-cell transplantation

FM Marty, P Ljungman, RF Chemaly… - … England Journal of …, 2017 - Mass Medical Soc
… , 22 letermovir at a dose of 240 mg per day was highly effective in preventing CMV viremia
after engraftment in transplant … of letermovir for CMV prophylaxis after transplantation in CMV-…

Cytomegalovirus-specific T-cell reconstitution following letermovir prophylaxis after hematopoietic cell transplantation

D Zamora, ER Duke, H Xie, BC Edmison… - Blood, The Journal …, 2021 - ashpublications.org
… debut of letermovir as standard CMV prophylaxis in … letermovir prophylaxis, and had no
reactivated CMV requiring preemptive antiviral therapy before initiation of letermovir prophylaxis. …

Letermovir for primary and secondary cytomegalovirus prevention in allogeneic hematopoietic cell transplant recipients: Real‐world experience

A Lin, M Maloy, Y Su, V Bhatt… - Transplant Infectious …, 2019 - Wiley Online Library
… with letermovir, we show that primary letermovir prophylaxis was efficacious in preventing
CMV infection in CMV … Only 2 (5%) of 39 patients who received primary letermovir prophylaxis

Refractory and resistant cytomegalovirus after hematopoietic cell transplant in the letermovir primary prophylaxis era

J Sassine, F Khawaja, TL Shigle… - Clinical Infectious …, 2021 - academic.oup.com
… in clinically significant CMV infections (CS-CMVi) in clinical trials of CMV-… letermovir
prophylaxis in this population on the incidence and outcomes of refractory or resistant CMV

Letermovir prophylaxis for cytomegalovirus infection in children after hematopoietic cell transplantation

M Richert-Przygonska, K Jaremek, R Debski… - Anticancer …, 2022 - ar.iiarjournals.org
… significant CMV reactivation. While letermovir has been approved for prophylactic use in CMV
… The objective of the study was to examine the use of letermovir for prophylaxis from CMV

A mortality analysis of letermovir prophylaxis for cytomegalovirus (CMV) in CMV-seropositive recipients of allogeneic hematopoietic cell transplantation

P Ljungman, M Schmitt, FM Marty… - Clinical Infectious …, 2020 - academic.oup.com
Cytomegalovirus (CMV) infection and disease remain clinically important complications after
allogeneic hematopoietic cell transplantation (… the effects of letermovir prophylaxis on all-…

Efficacy of prophylactic letermovir for cytomegalovirus reactivation in hematopoietic cell transplantation: a multicenter real-world data

Y Mori, F Jinnouchi, K Takenaka, T Aoki… - … Marrow Transplantation, 2021 - nature.com
… -cytomegalovirus (CMV) agent, letermovir (LMV), could reportedly improve the outcomes of
allogeneic hematopoietic cell transplantation … potential to prevent CMV reactivation. Therefore…

Clinical “real‐world” experience with letermovir for prevention of cytomegalovirus infection in allogeneic hematopoietic cell transplant recipients

A Anderson, M Raja, N Vazquez, M Morris… - … transplantation, 2020 - Wiley Online Library
… real-world data on the efficacy and safety of letermovir. Here, we describe our single-center
experience using letermovir for CMV prophylaxis among high-risk allogeneic HCT recipients. …

Impact of letermovir primary cytomegalovirus prophylaxis on 1-year mortality after allogeneic hematopoietic cell transplantation: a retrospective cohort study

Y Su, A Stern, E Karantoni, T Nawar… - Clinical Infectious …, 2022 - academic.oup.com
… ) hematopoietic cell transplant (HCT) recipients have a survival disparity compared with CMV-…
We hypothesized that primary letermovir prophylaxis (LET) may abrogate this disparity. We …

Letermovir for secondary prophylaxis of cytomegalovirus infection and disease after allogeneic hematopoietic cell transplantation: results from the French …

C Robin, A Thiebaut, S Alain, FS de Fontbrune… - … Marrow Transplantation, 2020 - Elsevier
Letermovir primary prophylaxis given for the first 3 months after allogeneic hematopoietic
cell transplantation (HCT) has been shown to reduce clinically significant CMV infection and is …