… cell surface bound EVs prior to imaging the cells. At 37 C, PKH26-labeled EVs internalized
into cells … methodology remains relevant to evaluate any potential EV biocorona differences. …

… of the rationale for developing radiolabeled sdAbs for RPT … the ratio of internalized fraction
over surface bound fraction, … which has incorporated several distinguishing design features: a …

… bound) is usually utilized to identify the cellular uptake of … to injection with the radiolabelled
antibody. Eventually this has … the total cell binding capacity (internalized and surface bound) …

… (immunoPET) can identify targets for cell-signaling independent … Cell surface-bound radiotracer
was collected by cells … Internalized fraction was obtained after cell lysis with 1 M sodium …

… of the adaptive immune system to recognize and neutralize … (169) After surface-bound
antibodies capture C1q, a cascade … to the internalization and elimination of antibodies should also …

… All other measured SUV values did not show a statistically significant difference. Tumor to
… 50 mM glycine (pH 2.8) to remove surface-bound radioactivity. The internalized fraction was …

… significant difference in the binding affinity of the BCMA antibody, … , the cell uptake (sum of
internalized and surface-bound … The limitation of this study is the use of a subcutaneous tumor …

… 3d, blue surface) and overlap with the surface bound by EGF (Fig… -158 triggers EGFR
internalization and degradation in an … . The immunoreactivity of the antibody after radiolabeling …

… FAPα, which is a cell surface-bound type II transmembrane … analysis, except a slight difference
between the uptake values of … with no internalization that limits their function for efficient …

… We investigated whether there were measurable differences in the uptake of … of Cy5.5
fluorescence in cell lysates; B- fractional content of surface-bound and internalized AuNP-aptamer-…