… , and can be used to distinguish cancer from normal tissue. A variety … (GGT), a cell-surface-bound
enzyme overexpressed in … in the low-pH environment of lysosomes after internalization …

… All other measured SUV values did not show a statistically significant difference. Tumor to
… 50 mM glycine (pH 2.8) to remove surface-bound radioactivity. The internalized fraction was …

… 3d, blue surface) and overlap with the surface bound by EGF (Fig… -158 triggers EGFR
internalization and degradation in an … . The immunoreactivity of the antibody after radiolabeling …

… In order to identify their relative stability of the chelator-Fe(III) … internalized by B16F10 cells
within the first 15 min, and the … After removal of the surface-bound fraction, cell pellets were …

… Here we identify the uncharacterized … antibody and allowed to internalize for 30 min at 37
C as described in a. Remaining cell-surface bound antibody was stripped by washing in pH 2.5 …

… We investigated whether there were measurable differences in the uptake of … of Cy5.5
fluorescence in cell lysates; B- fractional content of surface-bound and internalized AuNP-aptamer-…

… in this work—which provides further advantages for this product [25]. … In addition, in this case,
no significant difference was … and was internalized into the tumor cells according to in vitro …

… especially when the tracer is internalized inside the cells. … , pH = 2.8) to remove surface bound
radioactive ligand. Thereafter, the … whether it can differentiate between high and low c-Met-…

… and biodistribution challenges, which limit their overall clinical … not distinguish between
normal healthy proliferating cells … at least one internal aqueous compartment surrounded by one …

… This antibody has been radiolabeled with various isotopes, … The resulting mixture was
extracted with EtOAc (50 mL × 3). The … buffer to separate surface bound from internalized (dashed …