… surface-bound particles and lysed to isolate internalized … out to identify the subset of clones
capable of internalization and … in situ brain perfusion of radiolabeled anti-TfR antibody in rats, …

… lower cellular internalization with a maximum internalization … Remarkable differences were
observed for the radiobiological … to the cell–surface bound radioactivity was collected. The …

… dendrimers can be internalized as short as 20 min [43]. … to the NPs via the surface bound
opsonins. In addition, non-… and differences in permeability of blood vessels can cause a low …

… of the radiotracer due to differences between species. The … the bispecific antibodies and
radiolabeled haptens are usually low (< … Internalization of the TCO-tagged antibody after antigen …

… a decrease in internalization at 4 C (right) in all cell lines. (A) … performed on separate groups
of AsPC-1 cells exposed for 48 … Surface-bound activity was removed by washing the cells in …

… have been developed to routinely identify cyclic peptides as potent… A major limitation of this
method was that the cyclic peptide … internalization is provided by the use of HS-deficient CHO …

… , the cellular uptake (internalized and surface-bound radioactivity… To separate radiolabeled
peptides from unlabeled peptides … ) C18 high-performance extraction disk followed by elution …

… and radiolabeled mAb clones that specifically recognize human … secondary antibody for 1
hour at 4 C to measure non-internalized CD103-… only bind to surface bound CD103 mAbs. (3) …

… However, radiolabeled antibodies possess certain limitations … differences in cell viability as
a function of cell-internalized … from the other two forms by extraction in an organic phase (7:3 v/…

… K for 30 minutes to remove cell surface-bound aptamers. … Next, we analyzed aptamer
ability to recognize the soluble … binding with radiolabeled aptamer. The background values …