[HTML][HTML] Comparison of bacterial lipopolysaccharide-induced sickness behavior in rodents and humans: Relevance for symptoms of anxiety and depression

J Lasselin, M Schedlowski, B Karshikoff… - Neuroscience & …, 2020 - Elsevier
… This approach attempts to assess sickness behavior subjectively by addressing, for instance,
fatigue, reduced appetite and social disengagement. For example, the recently developed …

Repeated lipopolysaccharide exposure modifies immune and sickness behaviour response in an animal model of chronic inflammation

K Musaelyan, S Aldridge, A Du Preez… - Journal of …, 2018 - journals.sagepub.com
… , plasma cytokine profile, and the state of adult hippocampal neurogenesis and microglial
activation in the hippocampus were assessed weekly or at the end of six weekly injections in …

[HTML][HTML] Propentofylline prevents sickness behavior and depressive-like behavior induced by lipopolysaccharide in rats via neuroinflammatory pathway

MMT Moraes, MC Galvao, D Cabral, CP Coelho… - PLoS …, 2017 - journals.plos.org
… Neither LPS nor propentofylline has influenced the anxiety and … First, we evaluated sickness
behavior induction and … This shows that the effect of LPS inducing sickness behavior and …

[HTML][HTML] The effects of Nigella sativa on sickness behavior induced by lipopolysaccharide in male Wistar rats

F Norouzi, A Abareshi, A Anaeigoudari… - Avicenna Journal of …, 2016 - ncbi.nlm.nih.gov
… Systemic injection of LPS induces a spectrum of behavior … as an explanation of anxiety-like
behaviors after LPS injection as … frequently used to evaluate the anxiety and depression in the …

Inducible nitric oxide synthase plays a role in depression-and anxiety-like behaviors chronically induced by lipopolysaccharide in rats: Evidence from inflammation …

F Beheshti, M Hashemzehi, M Hosseini… - Behavioural brain …, 2020 - Elsevier
behavioral tests. It was previously shown that LPS induces depression- and anxiety-like
behaviors … In the present research, the adverse effects of AG were not evaluated, but no mortality …

[HTML][HTML] The effects of captopril on lipopolysaccharide-induced sickness behaviors in rats

A Abareshi, A Anaeigoudari, F Norouzi… - Veterinary Research …, 2019 - ncbi.nlm.nih.gov
… EPM is a well-known tool frequently employed for the evaluation of anxiety-like behaviors
in … , LPS induced a sickness behavior presented by depression- and anxiety-like behaviors

Intranasal lipopolysaccharide administration prevents chronic stress-induced depression-and anxiety-like behaviors in mice

Q Lu, H Xiang, H Zhu, Y Chen, X Lu, C Huang - Neuropharmacology, 2021 - Elsevier
… We next evaluated the effect of a single intranasal LPS administration on CSDS-… anxiety-like
behaviors, we still do not know which types of cells mediate that effect of LPS. In the past …

Mood disturbance during experimental endotoxemia: predictors of state anxiety as a psychological component of sickness behavior

J Lasselin, S Elsenbruch, M Lekander… - Brain, behavior, and …, 2016 - Elsevier
… step, we tested the associations between the LPS-induced state … anxiety as an indicator
of the behavioral sickness response to LPS, we did not include other emotional or behavioral

Lipopolysaccharide induced anxiety-and depressive-like behaviour in mice are prevented by chronic pre-treatment of esculetin

K Sulakhiya, GP Keshavlal, BB Bezbaruah… - Neuroscience …, 2016 - Elsevier
… activity of ESC, the present study was initiated to evaluate the effect of chronic pre-treatment
of ESC against LPS-induced anxiety- and depressive-like behaviour in mice. …

Repeated daily administration of increasing doses of lipopolysaccharide provides a model of sustained inflammation-induced depressive-like behaviour in mice that is …

RA Wickens, L Ver Donck, AB MacKenzie… - Behavioural Brain …, 2018 - Elsevier
… We found that in adult C57BL/6J mice, acute LPS induced profound sickness behaviour but,
… in LPS-induced depressive-like behaviours. We found that sickness behaviour, as assessed