… patients with subjective or objective cognitive impairment who underwent neurological, CSF
biomarker … ) and T1-weighted MRI examinations at Kuopio University Hospital. We assessed …

… Longitudinal changes of biomarkers among different stages were … rates of change to calculate
the biomarker trajectories in … information), but CSF tau in patients with dementia due to AD …

… Although we could not detect a longitudinal change in t-tau and p-tau levels in our study…
change in the trajectories of tau markers in the dementia phase of AD. The decreases in the CSF …

… We used the symmetrized percent change (spc) to evaluate longitudinal changes in CTh,
calculated as the rate of thickness change (CTh at time2 – CTh at time1) divided by the …

… in the longitudinal change in biomarkers, we find modest but measurable group-wise changes
in AD CSF biomarkers … Importantly, we find that the longitudinal profile in patients with PD …

… Regarding the longitudinal change in both the AFE-T and the … reserve) and biological (AD
CSF biomarkers) data and the … relationships between the longitudinal memory performance (…

… The aim of this work is to characterize longitudinal changes, computed in a two-year period,
… and to seek for linear associations between baseline CSF biomarker levels (Aβ 42 , p-tau …

… Longitudinal changes in levels of CSF α-syn and other … , p-tau, and Aβ42 in CSF samples of
patients with PD and healthy … these core CSF biomarkers would be stable in patients with PD …

… patterns of within-person longitudinal change in a variety of … [SNAP-25]) CSF neuronal injury
biomarker levels in individuals … changes with regional brain atrophy and cognitive decline. …

… Our finding that both cross-sectional and longitudinal associations of memory … that memory
tests may have some value as a screen for the presence of abnormal CSF biomarkers. In …