The Role of T-Cadherin (CDH13) in Treatment Options with Garcinol in Melanoma

S Staebler, S Hoechst, A Thongmao, N Schneider… - Cancers, 2024 - mdpi.com
… to show that T-cadherin is a tumor suppressor lost in melanoma … cell lines and also melanomas
still express T-cadherin in … induces apoptosis in oral squamous cell carcinoma (OSCC) […

[HTML][HTML] T-Cadherin Expression in Actinic Keratosis Transforming to Invasive Squamous Cell Carcinoma

SA Buechner, TJ Resink - Dermatopathology, 2019 - karger.com
… Conclusions: T-cadherin-negative iSCC arises from AK showing partial or extensive regional
loss of T-cadherin in the basal layer of the epidermis. We speculate that T-cadherin loss in …

[HTML][HTML] T-cadherin expression in the epidermis and adnexal structures of normal skin

S Buechner, P Erne, TJ Resink - Dermatopathology, 2017 - karger.com
loss of T-cadherin expression in the suprabasal layers of epidermis (arrowheads; a). Strongly
positive expression of T-cadherin on endothelial cells of dermalsquamous cell carcinoma (…

The functional roles of T-cadherin in mammalian biology

J Sternberg, M Wankell, VN Subramaniam… - AIMS Molecular …, 2017 - eprints.qut.edu.au
… region of CDH13 and represses T-cadherin expression in melanoma … trafficking in cutaneous
squamous carcinoma cells. Genes … : implication of H-cadherin in prostate tumorigenesis. …

Tcadherin in prostate cancer: relationship with cancer progression, differentiation and drug resistance

B Dasen, T Vlajnic, C Mengus, C Ruiz… - The Journal of …, 2017 - Wiley Online Library
T-cadherin (CDH13 or H-cadherin) is an atypical member of the … of T-cadherin gene
expression due to allelic loss of … 55, but downregulated in squamous cell carcinoma and …

Cadherins and their role in malignant transformation: implications for skin cancer progression

ME Janik, D Hoja-Łukowicz… - Human Skin Cancer …, 2016 - books.google.com
… In normal skin, the expression of Tcadherin is mostly limited … due to the repression of CDH13
promoter activity by BRN2 … activity; gain or loss of Tcadherin expression switches EGFR …

T-cadherin inhibits invasion and migration of endometrial stromal cells in endometriosis

Q Lu, Y Huang, J Wu, Y Guan, M Du, F Wang… - Human …, 2020 - academic.oup.com
T-cadherin (T-cad), also named H-cadherin, is coded by the CDH13 gene. … the long arm
of human chromosome 16q24, which is a region where allele loss often occurs in many tumors. …

Update on the molecular pathology of cutaneous squamous cell carcinoma

EC Cozma, LM Banciu, C Soare… - International Journal of …, 2023 - mdpi.com
… and epigenetic changes and progress to cutaneous squamous cell carcinoma in situ (SCCIS)
and … to loss of function CDH13 gene promoter (T-cadherin gene promoter) T-cadherin Cell

Adhesion molecules in non-melanoma skin cancers: a comprehensive review

J Pogorzelska-Dyrbus, JC Szepietowski - in vivo, 2021 - iv.iiarjournals.org
… Although low expression of T-cadherin has been observed in … ICAM expression on NMSC
revealed lack of expression on … risk in primary cutaneous squamous cell carcinomas but are …

[HTML][HTML] Cadherin 13 inhibits pancreatic cancer progression and epithelial-mesenchymal transition by Wnt/β-catenin signaling

D Xu, H Yuan, Z Meng, C Yang, Z Li, M Li… - … of Cancer, 2020 - ncbi.nlm.nih.gov
… Cadherin 13 (CDH13, also known as T-cadherin or H-cadherin… of tumor cells derived from
glioma, cutaneous squamous cell … The loss or low expression of CDH13 has been observed in …