Regional tidal lung strain in mechanically ventilated normal lungs

LF Paula, TJ Wellman, T Winkler… - Journal of Applied …, 2016 - journals.physiology.org
… strain as the tidal change in regional volume referred to the regional gas volume at end-…
of regional metabolic activity, a marker of neutrophilic inflammation, during mechanical …

[HTML][HTML] Lung metabolism and inflammation during mechanical ventilation; an imaging approach

M Pourfathi, M Cereda, S Chatterjee, Y Xin… - Scientific Reports, 2018 - nature.com
… stretch, ARDS patients are managed in the ICU through protective ventilation with low tidal
volumes (V … Furthermore, we did not observe any changes in cardiac metabolic activity (Fig. 7) …

Low tidal volumes for everyone?

CR Rackley, NR MacIntyre - Chest, 2019 - Elsevier
… low tidal volume ventilation in all patients with lung injury or undergoing mechanical ventilation
… Among these are metabolic demands, pain (including presence of endotracheal tube), …

[HTML][HTML] Respiratory mechanics in patients with acute respiratory distress syndrome

V Russotto, G Bellani, G Foti - Annals of translational medicine, 2018 - ncbi.nlm.nih.gov
Lung regional metabolic activity and gas volume changes induced by tidal ventilation in
patients with acute lung injury. Am J Respir Crit Care Med 2011;183:1193-9. 10.1164/rccm.…

[HTML][HTML] Tidal volume in acute respiratory distress syndrome: how best to select it

M Umbrello, A Marino, D Chiumello - Annals of Translational …, 2017 - ncbi.nlm.nih.gov
Lung regional metabolic activity and gas volume changes induced by tidal ventilation in
patients with acute lung injury. Am J Respir Crit Care Med 2011;183:1193-9. 10.1164/rccm.…

Gradually increasing tidal volume may mitigate experimental lung injury in rats

NS Felix, CS Samary, FF Cruz, NN Rocha… - …, 2019 - pubs.asahq.org
… This study hypothesized that, in experimental mild acute respiratory distress syndrome,
lung damage caused by high tidal volume (V T ) could be attenuated if V T increased slowly …

Different tidal volumes may jeopardize pulmonary redox and inflammatory status in healthy rats undergoing mechanical ventilation

LS Cândido, NA de Matos, TF Castro… - Oxidative Medicine …, 2021 - Wiley Online Library
… 15], damaging cellular metabolism regulation and oxidizing … changes induced by high tidal
volume in the pulmonary parenchyma were associated with oxidant agents damaging the lung

Mechanical ventilation to minimize progression of lung injury in acute respiratory failure

L Brochard, A Slutsky, A Pesenti - American journal of respiratory …, 2017 - atsjournals.org
… , even before the start of insufflation because of regional (… from one region of lung to another
without a gain in tidal volume). … is principally caused by lung receptor stimulation, metabolic

Comparative effects of volutrauma and atelectrauma on lung inflammation in experimental acute respiratory distress syndrome

A Güldner, A Braune, L Ball, PL Silva… - Critical care …, 2016 - journals.lww.com
… control lung was not submitted to tidal ventilation, and lung … Second, we used a measure of
regional metabolic activity as … Third, we also did not assess the histologic changes induced by …

Respiratory drive in critically ill patients. Pathophysiology and clinical implications

K Vaporidi, E Akoumianaki, I Telias… - … journal of respiratory …, 2020 - atsjournals.org
… Although metabolic rate plays a key role in modulating the respiratory drive during
exercise, … sedated patients with high tidal volumes. Am J Respir Crit Care Med 2017;195:1033–1042. …