The multifaceted role of CD4+ T cells in CD8+ T cell memory

BJ Laidlaw, JE Craft, SM Kaech - Nature Reviews Immunology, 2016 - nature.com
… You are using a browser version with limited support for CSS. … T cells in the regulation of
memory CD8 + T cell differentiation. … for the generation of functional memory CD8 + T cells 45 , …

[HTML][HTML] Defining memory CD8 T cell

MD Martin, VP Badovinac - Frontiers in immunology, 2018 - frontiersin.org
… basic level, a memory CD8 T cell can be defined as a CD8 T cell … on memory CD8 T cells
generated in response to infection. … generation of long-lasting circulating effector memory (Tem) …

Modulation of asymmetric cell division as a mechanism to boost CD8+ T cell memory

M Borsa, I Barnstorf, NS Baumann, K Pallmer… - Science …, 2019 - science.org
Using the murine LCMV infection model, we established a … linked to cell stemness, as only
naïve and memory CD8 + T cells could … memory T cell generation in adoptive transfer settings. …

Origin and differentiation of human memory CD8 T cells after vaccination

RS Akondy, M Fitch, S Edupuganti, S Yang, HT Kissick… - Nature, 2017 - nature.com
… Here we address this issue using the live yellow fever virus (YFV) vaccine… viral infection, and
to examine the generation and … rate and longevity of human memory CD8 T cells generated …

[PDF][PDF] CD8+ T cell priming in established chronic viral infection preferentially directs differentiation of memory-like cells for sustained immunity

LM Snell, BL MacLeod, JC Law, I Osokine… - Immunity, 2018 - cell.com
… CD4+ T cell help for its functional generation. Chronic viral … The role of priming DC was
further corroborated using infection … the memory CD8+ T cell pathway was enriched in Tlp cells (…

CD8+ T cell metabolism in infection and cancer

M Reina-Campos, NE Scharping… - Nature Reviews …, 2021 - nature.com
… killing of infected cells, while long-lived memory CD8 + T cellusing this in vitro system
suggested that memory CD8 + T … to couple oxidative phosphorylation with the generation of ATP …

[HTML][HTML] CD4+ T cell help creates memory CD8+ T cells with innate and help-independent recall capacities

T Ahrends, J Busselaar, TM Severson, N Bąbała… - Nature …, 2019 - nature.com
T cell help on the generation of memory CD8 + T cell subsets in a model of overt inflammation.
Mice were infected with the acute … the replicates for each cell type using samtools and …

[HTML][HTML] On the Role of CD8+ T Cells in Determining Recovery Time from Influenza Virus Infection

P Cao, Z Wang, AWC Yan, J McVernon, J Xu… - Frontiers in …, 2016 - frontiersin.org
… ) is only capable of generating a transient decrease in viral … CD8 + T cells in clearing influenza
virus from the host using a … We also investigated the effect of memory CD8 + T cell level

[PDF][PDF] Constitutive glycolytic metabolism supports CD8+ T cell effector memory differentiation during viral infection

AT Phan, AL Doedens, A Palazon, PA Tyrakis… - Immunity, 2016 - cell.com
… oxidative phosphorylation in memory CD8+ T cell formation, we … Using this model, we tested
the impact of constitutive … to acute infection, we demonstrated that the generation of SRC …

[HTML][HTML] Human T cell memory: A dynamic view

DC Macallan, JAM Borghans, B Asquith - Vaccines, 2017 - mdpi.com
using in vivo stable isotope labelling has shown that memory … across T cell populations [36],
or results from the generation of a … and survival rates of memory CD8 + T cells through an M-…