The postnatal leptin surge in mice is variable in both time and intensity and reflects nutritional status

AA Skowronski, ED Shaulson, RL Leibel… - International Journal of …, 2022 - nature.com
… We determined how the leptin surge is affected by early over- or undernutrition and maternal
HFD … Our data indicate that in mice, nutritional status during the perinatal period is critical in …

[PDF][PDF] SAT-287 Mild Perinatal Undernutrition Results in Underweight Pups and a Premature Neonatal Leptin Surge

TK Miles, ML Allensworth, ARS Moreira… - Journal of the …, 2020 - academic.oup.com
… if the timing of the leptin surge had shifted. This maternal undernutrition study consisted of
… reduction in nutrition will negatively impact offspring and shift the timing of the leptin surge. …

Perinatal nutrition and programming of the hypothalamic regulation of feeding behavior and Energy homeostasis

F Bolaños-Jimenez, R Mercado-Camargo… - … and Early Postnatal …, 2017 - taylorfrancis.com
Maternal perinatal undernutrition drastically reduces postnatal leptin surge and affects
the development of arcuate nucleus proopiomelanocortin neurons in neonatal male rat pups…

[图书][B] Altered Leptin Signaling: The Impact of Caloric Restriction on the Anterior Pituitary of Neonatal and Adult Mice

TK Miles - 2020 - search.proquest.com
… The mild maternal undernutrition resulted in altered postnatal GH secretion at PND1 and …
the effect of perinatal undernutrition on the neonatal leptin surge and its ultimate effect on …

[HTML][HTML] Postnatal undernutrition delays a key step in the maturation of hypothalamic feeding circuits

AJ De Solis, AF Baquero, CM Bennett, KL Grove… - Molecular …, 2016 - Elsevier
… There is a surge in leptin levels in the first two weeks of … Several different strategies
involving reductions in maternal and/… the impact of postnatal UN on the subpopulation of leptin-…

… : reduced maternal nutrition during early-to mid-gestation elevates newborn lamb plasma cortisol concentrations and eliminates the neonatal leptin surge

AM Smith, CL Pankey, JF Odhiambo… - Journal of animal …, 2018 - academic.oup.com
… The leptin surge, seen in CON lambs on postnatal days 8 to … born to undernourished or
overfed/obese mothers indicates … Further, the impact of cortisol on adipocyte differentiation and …

Hypothalamic effects of neonatal diet: reversible and only partially leptin dependent

L Sominsky, I Ziko, TX Nguyen, J Quach, SJ Spencer - 2017 - dro.deakin.edu.au
… C, Lesage J & Vieau D 2008 Maternal perinatal undernutrition drastically reduces postnatal
leptin surge and affects the development of arcuate nucleus proopiomelanocortin neurons in …

Mechanisms mediating the impact of maternal obesity on offspring hypothalamic development and later function

IC Furigo, L Dearden - Frontiers in endocrinology, 2022 - frontiersin.org
… The post-natal leptin surge can be altered by the perinatal … prolonged leptin surge magnitude
(46, 80). Conversely, the … surge, whereas large litter size- a model of under-nutrition- is …

The role of leptin in the development of energy homeostatic systems and the maintenance of body weight

CA LeDuc, AA Skowronski, M Rosenbaum - Frontiers in physiology, 2021 - frontiersin.org
Perinatal maternal undernutrition drastically reduces the postnatal surge of plasma leptin, …
of the offspring may be mediated through effects on the postnatal leptin surge which, in turn, …

Mechanisms mediating the impact of maternal obesity on offspring hypothalamic development and function

L Dearden - 2023 - repository.cam.ac.uk
Maternal perinatal undernutrition drastically reduces postnatal leptin surge and affects
the development of arcuate nucleus proopiomelanocortin neurons in neonatal male rat pups. …