How to characterize stem cells? Contributions from mathematical modeling
T Stiehl, A Marciniak-Czochra - Current Stem Cell Reports, 2019 - Springer
… of stem cell dynamics in vivo. This review explores how mathematical models can help to
characterize stem cell … Right: Cancer stem cell traits relevant to understand cancer progression, …
characterize stem cell … Right: Cancer stem cell traits relevant to understand cancer progression, …
Mathematical modeling of normal and cancer stem cells
LD Weiss, NL Komarova… - Current Stem Cell Reports, 2017 - Springer
… of stem cell dynamics. In this article, we review recent findings from mathematical models of
stem cell behavior. We focus on three aspects of stem cell dynamics: The role of stem cells in …
stem cell behavior. We focus on three aspects of stem cell dynamics: The role of stem cells in …
Control in dormancy or eradication of cancer stem cells: Mathematical modeling and stability issues
… For the sake of simplicity, we assume that unhealthy cells are those presenting mutations
that lead to cancer. Indeed, we consider that abnormal stem cells (Category B) have for …
that lead to cancer. Indeed, we consider that abnormal stem cells (Category B) have for …
A mathematical model for IL-6-mediated, stem cell driven tumor growth and targeted treatment
… a mathematical model for IL-6 mediated, cancer stem cell … the molecular level—capturing
cell surface dynamics of receptor-… Below we develop a mathematical model for cancer stem cell…
cell surface dynamics of receptor-… Below we develop a mathematical model for cancer stem cell…
The cancer stem cell fraction in hierarchically organized tumors can be estimated using mathematical modeling and patient-specific treatment trajectories
… population in human cancers remains unknown at any stage of the disease. We develop a
parameter-free mathematical model that allows estimation of cancer stem cell fractions from …
parameter-free mathematical model that allows estimation of cancer stem cell fractions from …
Fractional-order mathematical modelling of cancer cells-cancer stem cells-immune system interaction with chemotherapy
F Özköse, MT Şenel, R Habbireeh - Mathematical Modelling and …, 2021 - dergipark.org.tr
… a mathematical model of stem cells and chemotherapy for cancer treatment, in which the
model is … In addition, in order to point out the advantages of the fractional order modeling, the …
model is … In addition, in order to point out the advantages of the fractional order modeling, the …
MATHEMATICAL MODELING OF PANCREATIC CANCER TREATMENT WITH CANCER STEM CELLS
TA YILDIZ, E KÖSE, SL Elliott - Journal of Biological Systems, 2021 - World Scientific
… test the cancer stem cell theory under treatments, we incorporated the cancer stem cell
population in our model, … 59 We present the model with cancer stem cells for chemotherapy and …
population in our model, … 59 We present the model with cancer stem cells for chemotherapy and …
Modeling of interactions between cancer stem cells and their microenvironment: predicting clinical response
ME Sehl, MS Wicha - Cancer Systems Biology: Methods and Protocols, 2018 - Springer
… of the cancer stem cell niche, selection of the most appropriate mathematical model
remains challenging. We will describe a variety of mathematical modeling approaches and …
remains challenging. We will describe a variety of mathematical modeling approaches and …
HSC niche dynamics in regeneration, pre-malignancy, and cancer: insights from mathematical modeling
RK Pedersen, M Andersen, V Skov, L Kjær… - Stem Cells, 2023 - academic.oup.com
… engraftment of genetically engineered cells. We present a mathematical modeling approach
for studying the interactions between stem cells and niche cells (attachment, detachment, …
for studying the interactions between stem cells and niche cells (attachment, detachment, …
Cancer Stem Cell Division: Mathematical Models and Insights
ER Swanson, SL Elliott, EA Zollinger, E Kose - Current Stem Cell Reports, 2021 - Springer
… Here, we focus on the models that are relevant to the cancer stem cell division and … that
likely leads to tumor growth and recurrence. First, we explore the division of cells and then focus …
likely leads to tumor growth and recurrence. First, we explore the division of cells and then focus …