… A fundamental subdivision of nociceptive sensory neurons is named after their unique … of
TRPV1 mechanisms, several “mysteries” remain, ranging from the molecular mechanisms of …

… 2 receptor-mediated mechanisms are involved in the induction … of primary sensory neurons
(PSNs) with capsaicin, an effect not … ) is a non-pungent capsaicin- like compound found in low …

… sensory nerve endings and non-neurogenic TRPV1 effects due to its expression in cell types
other than sensory neurons… Molecular cloning of TRPV1 stimulated the search for new small…

… from small diameter sensory neurons in dorsal root ganglia … of effects on primary sensory
neurons function, from sensory … of 838 aminoacids, with a molecular weight of 95 kDa (…

… , and NFκBtranslocates and binds to DNA molecule. Then, the NFκB-DNA … activity for a
pathway inhibiting NFκB phosphorylation. Capsazepine was unable to inhibit capsaicin effects. …

… TRPV1 was identified in the central nervous system as well as in the sensory neurons of
the dorsal root ganglion [109]. At the level of the cardiovascular system, it can also be found in …

… built-in biological safety mechanisms that act as a … effect, a long-term sensory neuron
blocking action of capsaicin which can be used in the functional exploration of sensory neurons …

… a concise summary of the actions of capsaicin on sensory receptors, the mechanisms that
regulate the vanilloid receptor TRPV1 which is the molecular site of action for capsaicin. We …

… Thus, there is interest in developing capsaicin-like molecules devoid of the flaming sensation
while preserving the therapeutic action. Previously, we reported the design of soft drugs …

… Its effect is exerted by a particular molecular mechanism and … Capsaicin-like molecules,
known as capsaicin synthetic … This receptor was initially found on key sensory afferents neurons …