Natural products as mechanismbased anticancer agents: Sp transcription factors as targets

S Safe, R Kasiappan - Phytotherapy Research, 2016 - Wiley Online Library
… 2) exhibit anticancer activities in several different cancer cell lines and in vivo models and
have promising chemopreventive and chemotherapeutic activities (Gupta et al., 2014; Singh …

[HTML][HTML] Sulforaphane for the chemoprevention of bladder cancer: molecular mechanism targeted approach

A Leone, G Diorio, W Sexton, M Schell, M Alexandrow… - Oncotarget, 2017 - ncbi.nlm.nih.gov
agents for chemoprevention of bladder cancers. Adopting a systematic, molecular-mechanism
based approach, the goal of this review is to summarize epidemiological, in vitro, and …

In silico predictions on the possible mechanism of action of selected bioactive compounds against breast cancer

A Muhammad, BS Katsayal, GE Forcados… - In Silico …, 2020 - Springer
possible mechanism of action of these xenobiotics to guide in vitro and in vivo studies in
breast cancer… resources that could result in futile in vitro and in vivo experiments. Hence, in this …

Resveratrol for breast cancer prevention and therapy: Preclinical evidence and molecular mechanisms

D Sinha, N Sarkar, J Biswas, A Bishayee - Seminars in cancer biology, 2016 - Elsevier
drugs in various in vitro and in vivo models of breast cancer. … understanding the biology of
breast cancer. At present focus … of new therapies in a mechanism-based rational approach in …

[HTML][HTML] Role of phytochemicals in cancer chemoprevention: Insights

BP George, R Chandran, H Abrahamse - Antioxidants, 2021 - mdpi.com
possible use in the prevention of cancers over the years. The increasing volume of in vitro and
in vivo data on the cancer chemopreventive … CYP1B1 and a mechanism-based inhibitor of …

The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation

P Xi, Y Niu, Y Zhang, W Li, F Gao, W Gu, F Kui… - Journal of …, 2022 - Elsevier
… This study is to identify the prevention effect of dioscin on lung cancer and explore its key
mechanism based … Here, we reported that dioscin could prevent lung cancer in vitro and in vivo. …

Virtual screening of natural products to select compounds with potential anticancer activity

ÉBVS Cavalcanti, MB Félix, L Scotti… - Anti-Cancer Agents in …, 2019 - ingentaconnect.com
… have been identified or designed to develop as potential chemo-preventive agents [107]. …
demonstrated potential cancer chemoprevention in vitro and in vivo systems [119, 120]. …

Plant natural products: Promising resources for cancer chemoprevention

L Ma, M Zhang, R Zhao, D Wang, Y Ma, L Ai - Molecules, 2021 - mdpi.com
… Actually, there is an urgent need to develop the mechanism-based approaches/strategies …
Both in vivo and in vitro studies were involved in this review. The references of these articles …

Prostate cancer chemoprevention by dietary agents: advocating a personalized multi-agent approach

VM Adhami, H Mukhtar - Critical dietary factors in cancer chemoprevention, 2016 - Springer
… -agent approach could prove effective in preventing cancer in … of mechanism-based naturally
occurring chemopreventivevitro and in vivo studies assessing the role of dietary agents

Pomegranate peel and its anticancer activity: A mechanism-based review

T Usha, SK Middha, KR Sidhalinghamurthy - Plant-derived Bioactives …, 2020 - Springer
… The current chapter is aiming to understand various model systems (in silico, in vitro, and
in vivo), employed for studying its anti-cancerous properties and diverse molecular effects …