Protein interactions at oxidized 5-methylcytosine bases
… The biochemical regulation of TET protein-mediated 5mC oxidation is not completely
understood. When the enzymatic reaction proceeds beyond 5hmC, and 5fC or 5caC are formed, …
understood. When the enzymatic reaction proceeds beyond 5hmC, and 5fC or 5caC are formed, …
Epigenetic function of TET family, 5-methylcytosine, and 5-hydroxymethylcytosine in hematologic malignancies
W Li, L Xu - Oncology research and treatment, 2019 - karger.com
… functions of TET family … TET proteins can further iteratively oxidize 5-hmC to form 5-formylcytosine
(5-fC) and 5-carboxylcytosine (5-caC) [22, 23]. Over the past years, the function of TET …
(5-fC) and 5-carboxylcytosine (5-caC) [22, 23]. Over the past years, the function of TET …
[HTML][HTML] The emerging insights into catalytic or non-catalytic roles of TET proteins in tumors and neural development
H Lian, WB Li, WL Jin - Oncotarget, 2016 - ncbi.nlm.nih.gov
… TET-mediated DNA oxidation plays prominent roles in a … mechanisms, mainly including
DNA methylation such as covalent modification of cytosine bases leading to 5-methylcytosine (…
DNA methylation such as covalent modification of cytosine bases leading to 5-methylcytosine (…
MBD3L2 promotes Tet2 enzymatic activity for mediating 5-methylcytosine oxidation
L Peng, Y Li, Y Xi, W Li, J Li, R Lv… - Journal of cell …, 2016 - journals.biologists.com
… Tet) family, including Tet1, Tet2 and Tet3, are Fe(II)- and α-ketoglutarate (α-KG)-dependent
dioxygenases that oxidize 5-methylcytosine … of Tet regulation, indicating a potential role of the …
dioxygenases that oxidize 5-methylcytosine … of Tet regulation, indicating a potential role of the …
Label-free Raman observation of TET1 protein-mediated epigenetic alterations in DNA
X Luo, L Jiang, T Kang, Y Xing, E Zheng, P Wu… - Analytical …, 2019 - ACS Publications
… alterations in the TET protein-mediated oxidation process. … alterations in the TET
protein-mediated oxidation process, which … in S1 was replaced by 5-methylcytosine m CGC GCG …
protein-mediated oxidation process, which … in S1 was replaced by 5-methylcytosine m CGC GCG …
Regulation of RNA Methylation by TET Enzymes
KM Banks, T Evans - Epitranscriptomics, 2021 - Springer
… oxidizing 5-methylcytosine (m 5 C) to 5-hydroxymethylcytosine (hm 5 C) and further oxidized
… have demonstrated that m 5 C and TET protein-mediated oxidation are also important in the …
… have demonstrated that m 5 C and TET protein-mediated oxidation are also important in the …
Function determinants of TET proteins: the arrangements of sequence motifs with specific codes
D Liu, G Li, Y Zuo - Briefings in bioinformatics, 2019 - academic.oup.com
… of 5-methylcytosine (5mC) is actively reversed to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine
(5fC) and 5-carboxylcytosine (5caC) through TET dioxygenase-mediated oxidation […
(5fC) and 5-carboxylcytosine (5caC) through TET dioxygenase-mediated oxidation […
Deciphering the Role of TET2-mediated DNA Methylcytosine Oxidation in Cancer Immunotherapy
M Lee - 2020 - oaktrust.library.tamu.edu
… make up a new class of enzymes that successively oxidizes 5-methylcytosine (5mC) to 5-…
others have shown that Tet protein mediated DNA methylation oxidation regulates gene …
others have shown that Tet protein mediated DNA methylation oxidation regulates gene …
[HTML][HTML] TET protein inhibitors: Potential and limitations
R Kaplánek, Z Kejík, J Hajduch, K Veselá… - Biomedicine & …, 2023 - Elsevier
… TET proteins gradually convert 5-methylcytosine into 5-hydroxymethylcytosine, 5-formylcytosine, …
suggest that TET proteins could also be involved in the oxidation of 5-methylcytosine in …
suggest that TET proteins could also be involved in the oxidation of 5-methylcytosine in …
Wilms' Tumor protein 1 and enzymatic oxidation of 5-methylcytosine in brain tumors: potential perspectives
A Ramsawhook, A Ruzov, B Coyle - Frontiers in Cell and …, 2018 - frontiersin.org
… (C) Tet protein mediated oxidation of 5 mC to oxi-mC derivatives attracts oxi-mC reader
proteins WT1 and CHTOP competing for the same DNA binding sequence. (D) 5mC oxidation to …
proteins WT1 and CHTOP competing for the same DNA binding sequence. (D) 5mC oxidation to …