Insights into new mechanisms and models of cancer stem cell multidrug resistance

Y Garcia-Mayea, C Mir, F Masson, R Paciucci… - Seminars in cancer …, 2020 - Elsevier
… and resistant disease. Targeting resistant cancers is a major challenge in oncology; however…
and increase life expectancy, relapse and multidrug resistance (MDR) ultimately remain the …

New insights into antiangiogenic therapy resistance in cancer: Mechanisms and therapeutic aspects

M Huang, Y Lin, C Wang, L Deng, M Chen… - Drug resistance …, 2022 - Elsevier
… for tumor escape from antiangiogenic therapy. Currently, drug resistance has become the …
the cellular and molecular mechanisms conferring tumor drug resistance to antiangiogenic …

Novel insights on lipid metabolism alterations in drug resistance in cancer

R Yang, M Yi, B Xiang - Frontiers in cell and developmental biology, 2022 - frontiersin.org
… is closely related to drug resistance in tumor. Targeting lipid … drugs is a promising strategy
to overcome drug resistance. … about aberrant lipid metabolism in chemoresistant cancer, …

[HTML][HTML] Insights into molecular mechanisms of chemotherapy resistance in cancer

A Kar, S Agarwal, A Singh, A Bajaj, U Dasgupta - Translational Oncology, 2024 - Elsevier
… events and highlighting their contribution in sensitivity to chemotherapy will provide insights
into drug resistance mechanisms and uncover novel perspectives in cancer treatment. …

Molecular insights into cancer drug resistance from a proteomics perspective

Y An, L Zhou, Z Huang, EC Nice, H Zhang… - Expert review of …, 2019 - Taylor & Francis
… in proteomics studies on cancer drug resistance with an … (PTMs) play in the mechanisms
of cancer drug resistance. … in drug-resistant cancer is key to deciphering the mechanisms

Emerging insights of tumor heterogeneity and drug resistance mechanisms in lung cancer targeted therapy

ZF Lim, PC Ma - Journal of hematology & oncology, 2019 - Springer
drug resistance mechanisms following cancer targeted therapy. The EGFR-mutant model
of drug resistance in lung cancer … models of mechanisms of drug resistance known as …

New insights into Vinca alkaloids resistance mechanism and circumvention in lung cancer

Y Zhang, SH Yang, XL Guo - Biomedicine & pharmacotherapy, 2017 - Elsevier
… alkaloids resistance in lung cancer. Understanding the principle of the Vinca alkaloids in
clinical application and mechanisms of drug resistance will support individualized lung cancer

New insights into mechanisms of cisplatin resistance: from tumor cell to microenvironment

SH Chen, JY Chang - International journal of molecular sciences, 2019 - mdpi.com
… In summary, CDDP has demonstrated major clinical success in patients with various types
of cancer for more than two decades; however, drug resistance of tumor cells has remained …

Current perspectives on targeting PIM kinases to overcome mechanisms of drug resistance and immune evasion in cancer

T Malone, L Schäfer, N Simon, S Heavey… - Pharmacology & …, 2020 - Elsevier
cancer that can be driven by hypoxia in the tumour microenvironment and the important role
that aberrant PIM kinase activity plays in resistance mechanisms … an escape mechanism to …

Insights on recent approaches in drug discovery strategies and untapped drug targets against drug resistance

R Peraman, SK Sure, VNA Dusthackeer… - Future Journal of …, 2021 - Springer
… strategies and drug discovery approaches in the area of drug resistance among researchers…
the insights pertaining to new drug development against drug-resistant microbes. It includes …