… levels, as well as of how its loss of function results in breakdown of self-tolerance mechanisms
characterized by a broad and heterogeneous repertoire of autoimmune phenotypes. …

… , transport and self-tolerance mechanisms should function … proteins responsible for transport
and self-tolerance. In particular, … in studies of transport and self-tolerance and provides an …

… is the generation of receptors to “self” and consequent autoimmune disease. … mechanisms
have no way of predicting the “self” within which they develop. Consequently, self-tolerance …

… revealed several mechanisms of self-tolerance; however, which mechanisms operate in …
mechanisms were also active for T cell populations specific for endogenously expressed self …

… IgM that protects its respective self-targets from degradation. We refer to this novel mechanism
as adaptive tolerance. This article discusses the discovery of adaptive tolerance and the …

… ’ tolerant behavior (optimal, efficient and acceptable). The main results of the study is to develop
the mechanisms for formation of tolerant … -role development of tolerant behavior, creating …

… The main objective of this work is to provide a self-healing mechanism for a faulttolerant
WSN. The proposed mechanism tries to identify the faults in each individual component of …

… Self-tolerance, the state of unresponsiveness to self-tissues/… tolerance mechanisms,
and a breach of these mechanisms … against self-antigens and thereby regulate self-tolerance. …

… However, detailed information on the mechanisms that regulate TCR interaction with self
ligands is still poorly understood. For example, it remains unclear why CD25-deficient mice …

… to establish persistent self-tolerance. These mechanisms maintain self-tolerance by limiting
… self-specific T and B cells via intrinsic and extrinsic events. Immunoregulation is a dominant …