[HTML][HTML] Bisphenol A and its analogues: a comprehensive review to identify and prioritize effect biomarkers for human biomonitoring

V Mustieles, SC d'Cruz, S Couderq… - Environment …, 2020 - Elsevier
… for BPA, as well as to provide relevant mechanistic and … To the best of our knowledge, this is
the first effort to identify … feasibility of the biomarker together with its specificity, sensitivity, and …

[HTML][HTML] Implementation of effect biomarkers in human biomonitoring studies: A systematic approach synergizing toxicological and epidemiological knowledge

A Rodríguez-Carrillo, V Mustieles… - International Journal of …, 2023 - Elsevier
… to identify and implement a panel of validated effect biomarkers in European HBM studies. …
link exposure biomarkers to mechanistically validated effect and susceptibility biomarkers in …

Prospects for incorporation of epigenetic biomarkers in human health and environmental risk assessment of chemicals

G Jeremias, FJM Gonçalves, JL Pereira… - Biological …, 2020 - Wiley Online Library
… were identified as the most promising prognostic biomarkersbiomarker had 90% sensitivity
for stage 1 cancer across all subjects. … of epigenetic biomarkers, a more detailed mechanistic

Epigenetics as a mechanism linking developmental exposures to long-term toxicity

R Barouki, E Melén, Z Herceg, J Beckers, J Chen… - Environment …, 2018 - Elsevier
… to discuss in order to identify or support an epigenetic … Following some mechanistic insight,
we will specifically address cases … of EDCs that have been linked to increased susceptibility, …

Molecular responses to environmental contamination: enzyme and protein systems as indicators of chemical exposure and effect

JJ Stegeman, B Marius, RT Di Giulio, F Lars… - …, 2018 - taylorfrancis.com
… We emphasize that changes detected in individuals are of … systems respond to chemicals,
the sensitivity and specificity of the … Defining mechanistic origin of other effects that might occur …

Effects of pesticide exposure on the expression of selected genes in normal and cancer samples: Identification of predictive biomarkers for risk assessment

S Italia, S Vivarelli, M Teodoro, C Costa… - Environmental …, 2024 - Elsevier
… novel appropriate biomarkers biomarkers to facilitate early detection of adverse effects and
… based on their individual susceptibility to detrimental effects of pesticides. Furthermore, …

Molecular mechanisms of environmental exposures and human disease

H Wu, CM Eckhardt, AA Baccarelli - Nature reviews genetics, 2023 - nature.com
… that evaluate recently discovered molecular processes … , environmental exposure-related
disease susceptibility differs … function as a mechanistic link between chemical exposures and …

[HTML][HTML] Lead (Pb) and neurodevelopment: A review on exposure and biomarkers of effect (BDNF, HDL) and susceptibility

C Gundacker, M Forsthuber, T Szigeti, R Kakucs… - International Journal of …, 2021 - Elsevier
… toxicity” and “it is recommended to add a qualitative statement in the … exposure of the
European population furthermore requires the identification of effect and susceptibility biomarkers

[HTML][HTML] Individual and joint effects of phthalate metabolites on biomarkers of oxidative stress among pregnant women in Puerto Rico

AL Cathey, JL Eaton, P Ashrap, DJ Watkins… - Environment …, 2021 - Elsevier
… windows of susceptibility to phthalate exposure. Repeated ERS … approach to better understand
mechanistic pathways related to … Our study did not identify any individual metabolites as …

The importance of the biological impact of exposure to the concept of the exposome

KK Dennis, SS Auerbach, DM Balshaw… - Environmental …, 2016 - ehp.niehs.nih.gov
biomarker and biological effect can be demonstrated. Markers of susceptibility are commonly
defined … will provide us with biomarkers and mechanistic insights through pathway mapping…