Therapeutic intranasal instillation of allergen-loaded microbubbles suppresses experimental allergic asthma in mice

B Corthésy, G Bioley - Biomaterials, 2017 - Elsevier
decrease the frequency of CD4 T cells producing IL-5, IL-13, … IgE, IgA and IgG Ab titers
measured in BALs after one or two … The same molecular and cellular mediators have been …

[HTML][HTML] Pulmonary IFN-γ causes lymphocytic inflammation and cough hypersensitivity by increasing the number of IFN-γ-secreting T lymphocytes

Z Deng, W Ding, F Li, S Shen, C Huang… - Allergy, Asthma & …, 2022 - ncbi.nlm.nih.gov
… C (used for cytokine measurement), and … day for 7 consecutive days. Cough sensitivity was
detected in all the guinea pigs before the first intratracheal instillation and two days later after

Local (but not systemic) photobiomodulation treatment reduces mast cell degranulation, eicosanoids, and Th2 cytokines in an experimental model of allergic rhinitis

A Schapochnik, S Klein, R Brochetti, PT Alonso… - Lasers in Medical …, 2021 - Springer
… ) immediately after the last instillation of OVA (1%) daily for 3 … of molecular mediators, such
as interleukins IL-4, IL-5, and IL-… -4, and increased IL-10 without altering IL-5 or IFN-gamma. It …

[HTML][HTML] Neutralization of interleukin-9 ameliorates symptoms of allergic rhinitis by reducing Th2, Th9, and Th17 responses and increasing the Treg response in a …

ZW Gu, YX Wang, ZW Cao - Oncotarget, 2017 - ncbi.nlm.nih.gov
… reducing the levels of multiple inflammatory mediators therein. … IL-5 can stimulate the
development of eosinophils in the bone … nasal instillation of 100 μg OVA in 20 μL saline per …

[图书][B] Nasal allergen provocation: validation of clinical and immunologic markers and response to grass pollen immunotherapy

G Scadding - 2016 - core.ac.uk
… development of allergic rhinitis dependent on length of time … After instillation of 5% lidocaine
hydrochloride/0.5% … for mediator recovery than 111 SAMs for tryptase, ECP, IL-4, IL-5, IL-13 …

[HTML][HTML] Histamine and T helper cytokine–driven epithelial barrier dysfunction in allergic rhinitis

B Steelant, SF Seys, L Van Gerven… - Journal of Allergy and …, 2018 - Elsevier
… a key role for allergic inflammatory mediators in modulating … and is further orchestrated by
T H 2 cytokines IL-4, IL-5, and/or … One day after the last instillation, 20 μL FD4 (50 mg/mL) was …

Intranasal administration of IL-35 inhibits allergic responses and symptoms in mice with allergic rhinitis

M Suzuki, M Yokota, Y Nakamura, S Ozaki… - Allergology …, 2017 - jstage.jst.go.jp
… Regulatory T cells mediate maternal tolerance to the fetus.… , IL-5, and IL-10 cytokines, we
measured the level of IL-4, IL-5, … ū T cell responses, IFN-gamma production, and cytolytic activity …

Inhibition of allergic response by intranasal selective NF-κB decoy oligodeoxynucleotides in a murine model of allergic rhinitis

JH Wee, YL Zhang, CS Rhee… - Allergy, asthma & …, 2017 - synapse.koreamed.org
… related cytokine and inflammatory mediator genes expressions… were administered via daily
OVA instillation from days 20 to … symptom scores and levels of the Th2 cytokines IL-4 and IL-5

PGI2 controls pulmonary NK cells that prevent airway sensitization to house dust mite allergen

B Simons, ME Ferrini, S Carvalho… - The Journal of …, 2017 - journals.aai.org
instillation of the allergen induced markedly reduced levels … during allergic lung inflammation
(46) and this mediator is … type 2 cytokines IL-5 and IL-13 in allergic lung inflammation (64, …

Critical role of interleukin-23 in development of asthma promoted by cigarette smoke

HS Lee, DE Park, JW Lee, HN Kim, WJ Song… - Journal of Molecular …, 2019 - Springer
increased by CSE and Dp co-instillation. Anti-IL-23 or IL-23R antibody treatment during
allergen sensitization significantly diminished … and IL-5-positive CD4 + T cells were increased